›› 2010, Vol. 37 ›› Issue (9): 179-182.

• 疾病防治 • 上一篇    下一篇

Th17细胞及其与疾病的研究进展

滕素玲,邵悦,郑世民   

  1. (东北农业大学动物医学学院,哈尔滨 150030)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-09-20 发布日期:2010-09-20
  • 通讯作者: 郑世民

Progress of Th17 Cell and Disease

TENG Su-ling, SHAO Yue, ZHENG Shi-min   

  1. (College of Animal Medicine, Northeast Agricultural University, Harbin 150030,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-09-20 Published:2010-09-20
  • Contact: ZHENG Shi-min

摘要: 辅助性T细胞17(T help cell 17,Th17)是2005年新发现的能够分泌白细胞介素17的CD4+ T细胞,其与Th1、Th2、Tregs细胞共同构成CD4+ T细胞的4个亚群,该细胞与炎症、各种感染性疾病、肿瘤和自身免疫性疾病的发生密切相关。作者对Th17细胞及其在某些疾病或病理过程中作用的研究进展进行了简要综述。

关键词: Th17细胞; 白细胞介素-17; 疾病

Abstract: T help 17 (Th17) cell, which was first found in 2005 and is characterized by the release of interleukin (IL)-17, constitutes four subtypes of CD4+T cells together with Th1, Th2 and regulatory T (Tregs) cells. Th17 cell has a closely association with the development of inflammatory, infectious diseases, tumors and autoimmune diseases. In this paper, the roles of Th17 cell in certain disease or pathological process were summarized.

Key words: Th17 cell; interleukin-17; disease

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