1 于晨龙,张七斤,陈光明,等. 不同来源乳酸菌的分离与鉴定[J]. 中国畜牧兽医,2014,41(2):208~212.2 王振华. 动物黏膜免疫疫苗基因表达系统——乳酸菌的研究进展[J]. 中国畜牧兽医,2010,37(10):194~197.3 叶丽萍,郝凤奇,王春凤,等. 口服猪A组轮状病毒Vp4基因工程乳酸菌对BALB/c小鼠的免疫保护作用[J]. 中国兽医学报,2010,30(7):869~872.4 任贵强,张七斤,张和平,等. 饲喂乳酸菌对小鼠血清中IgG及肠道sIgA影响的研究[J]. 中国畜牧兽医,2006,33(5):64~67.5 孙建和,路平. 禽细胞因子的新功能——免疫治疗和疫苗佐剂[J]. 生物工程学报,2003,19(2):141~146.6 齐炳理,葛俊伟,乔薪瑗,等. 表达传染性腔上囊病毒VP2蛋白重组乳酸菌疫苗的构建及其免疫保护效果[J]. 中国兽医科学,2009,39(11):978~983.7 汪川,张朝武. 以益生菌为载体的基因工程疫苗研究进展[J]. 卫生研究,2008,37(1):118~122.8 阿木尔吉日嘎拉,任贵强,张七斤,等. 两株乳酸菌对鸡新城疫HI抗体效价影响的研究[J]. 中国畜牧兽医,2006,33(3):62~64.9 胡静涛,王春凤. 猪源A组轮状病毒重组质粒pW425et-Vp7在乳酸菌中的表达及免疫原性分析[J]. 微生物学报,2008,48(11):1514~1519.10 饶雷,黄武,黄永兴,等. 弯曲杆菌中具有高抑菌活性乳酸菌的筛选[J]. 中国畜牧兽医,2013,40(6):129~134.11 高荣琨,王昕,李文斌. 乳酸菌对及鸡免疫功能的影响[J]. 中国动物检疫,2009,26(12):39~40.12 温建新,邵峰,李志辉,等. 乳酸菌制剂对鸡新城疫HI抗体效价影响的研究[J]. 山东畜牧兽医,2007,23(2):22~24.13 黎敏,符海英. 细胞因子在畜禽疾病防治中的研究进展[J]. 广东农业科学,2010,4(2):201~204.14 Amit-Romach E, Sklan D, Uni Z. Microflora ecology of the chicken intestine using 16S ribosomal DNA primers[J]. Poultry Sci, 2004, 83(7): 1093~1098.15 Bermúdez-Humarán L G, Langella P, Cortes-Perez N G, et al. Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production[J]. Infect Immunity, 2003, 71(4): 1887~1896.16 Bermúdez-Humarán L G, Cortes-Perez N G, Lefèvre F, et al. A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors[J]. J Immunol, 2005, 175(11): 7297~7302.17 Bermúdez-Humarán L G. Lactococcus lactis as a live vector for mucosal delivery of therapeutic proteins[J]. Human Vaccines, 2009, 5(4): 264~267.18 Bermúdez-Humarán L G, Kharrt P, Chatel J M, et al. Lactococci and Lactobacilli as mucosal delivery vector for therapeutic proteins and DNA vaccines[J]. Mcirobial Cell Factories, 2011, 10(1): S4.19 Cao H P, Wang H N, Zhang A Y, et al. Expression of avian infectious bronchitis virus multi-epitope based peptide EpiC in Lactococcus lactis for oral immunization of chickens[J]. Biosci Biotechnol Biochem, 2012, 76(10): 1871~1876.20 Cao H P, Wang H N, Yang X, et al. Lactococcus lactis anchoring avian infectious bronchitis virus multi-epitope peptide EpiC induces specific immune responses in chickens[J]. Biosci Biotechnol Biochem, 2013, 77(7): 1~6.21 Cheung Q C K, Yuan Z F, Dyce P W, et al. Generation of epidermal growth factor-expressing Lactococcus lactis and its enhancement on intestinal development and growth of early-weaned mice[J]. Am J Clin Nutr, 2009, 89(3): 871~879.22 Cortes-Perez N G, da Costa-Medina L F, Lefèvre F, et al. Production of biologically active CXC chemokines by Lactococcus lactis: Evaluation of its potential as a novel mucosal vaccine adjuvant[J]. Vaccine, 2008, 26(46): 5778~5783.23 Dieye Y, Hoekman A J W, Clier F, et al. Ability of Lactococcus lactis to export viral capsid antigens: A crucial step for development of live vaccines[J]. Appl Environ Microbiol, 2003, 69(12): 7281~7288.24 Guimaraes V D, Gabriel J E, Lefevre F, et al. Internalin-expressing Lactococcus lactis is able to invade small intestine of guinea pigs and deliver DNA into mammalian epithelial cells[J]. Microbes Infect, 2005, 7(5): 836~844.25 Hou X L, Yu L Y, Liu J Z, et al. Surface-displayed porcine epidemic diarrhea viral (PEDV) antigens on lactic acid bacteria[J]. Vaccine, 2007, 26(1): 24~31.26 Hugentobler F, Roberto R B D, Gillard J, et al. Oral immunization using live Lactococcus lactis co-expressing LACK and IL-12 protects BALB/c mice against Leishmania major infection[J]. Vaccine, 2012a, 30 (39): 5726~5732.27 Hugentobler F, Yam K K, Gillard J, et al. Immunization against Leishmania major infection using LACK- and IL-12-expresing Lactococcus lactis induces delay in footpad swelling[J]. PLoS One, 2012b, 7(2): e30945.28 Innocentin S, Guimaraes V, Miyoshi A, et al. Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein A or Listeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells[J]. Appl Environ Microbiol, 2009, 75(14): 4870~4878.29 Kajikawa A, Satoh E, Leer R J, et al. Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis[J]. Vaccine, 2007, 25(18): 3599~3605.30 Kajikawa A, Zhang L, Long J, et al. Construction and immunological evaluation of dual cell surface display of HIV-1 gag and Salmonella enterica Serovar Typhimurium FliC in Lactobacillus acidophilus for vaccine delivery[J]. Clin Vaccine Immunol, 2012, 19(9): 1374~1381.31 Lee M H, Roussel Y, Wilks M. Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H.pylori infection in mice[J]. Vaccine, 2001, 19(28): 3927~3935.32 Lee J S, Poo H, Han D P, et al. Mucosal immunization with surface-displayed severe acute respiratory syndrome coronavirus spike protein on Lactobacillus casei induces neutralizing antibodies in mice[J]. J Virol, 2006, 80(8): 4079~4087.33 Lei H, Xu Y H, Chen J, et al. Immunoprotection against influenza H5N1 virus by oral administration of enteric-coated recombinant Lactococcus lactis mini-capsules[J]. Virol, 2010, 407(2): 319~324.34 Li X, Xing Y, Guo L, et al. Oral immunization with recombinant Lactococcus lactis delivering a multi-epitope antigen CTB-UE attenuates Helicobacter pylori infection in mice[J]. Pathog Dis, 2014, DOI: 10.1111/2049-632X. 12173.35 Lin K H, Hsu A P, Shien J H, et al. Avian reovirus sigma C enhances the mucosal and systemic immune responses elicited by antigen-conjugated lactic acid bacteria[J]. Vaccine, 2012, 30(33): 5019~5029.36 Liu J K, Hou X L, Wei C H, et al. Induction of immune responses in mice after oral immunization with recombinant Lactobacillus casei strains expressing enterotoxigenic Escherichia coli F41 fimbrial protein[J]. Appl Environ Microbiol, 2009, 75(13): 4491~4497.37 Loir Y L, Nouaille S, Commissaire J, et al. Signal peptide and propeptide optimization for heterologous protein secretion in Lactococcus lactis[J]. Appl Environ Microbiol, 2001, 67(9): 4119~4127.38 Loir Y L, Azevedo V, Oliveira S. Protein secretion in Lactococcus lactis: An efficient way to increase the overall heterologous protein production[J]. Microbial Cell Fact, 2005, 4: 2.39 Matthijs M G R, Ariaans M P, Dwars R M, et al. Course of infection and immune responses in the respiratory tract of IBV infected broilers after superinfection with E. coli[J]. Vet Immunol Immunopathol, 2008, 127(1): 77~84.40 Messaoudi S, Kergourlay G, Dalgalarrondo M, et al. Purification and characterization of a new bacteriocin active against camplybacter produced by Lactobacillus salivarius SMXD51[J]. Food Microbiol, 2012, 32(1): 129~134.41 Moal V L, Servin A L. Anti-infective activities of Lactobacillus strains in the human intestinal microbiota: From probiotics to gastrointestinal anti-infectious biotherapeutic agents[J]. Clin Microbiol Rev, 2014, 27(2): 167~199.42 Moeini H, Rahim R A, Omar A R, et al. Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virus[J]. Appl Microbiol Biotechnol, 2011, 90: 77~88.43 Moorthy G, Ramasamy R. Mucosal immunization of mice with malaria protein on lactic acid bacterial cell walls[J]. Vaccine, 2007, 25(18): 3636~3645.44 Pathangey L, Kohler J J, Isoda R, et al. Effect of expression level on immune responses to recombinant oral Salmonella enterica serovar Typhimurium vaccines[J]. Vaccine, 2009, 27(20): 2707~2711.45 Perez C A, Eichwald C, Burrone O, et al. Rotavirus vp7 antigen produced by Lactococcus lactis induces neutralizing antibodies in mice[J]. J Appl Mcrobiol, 2005, 99(5): 1158~1164.46 Poo H, Pyo H M, Lee T Y, et al. Oral administration of human papillomavirus type 16 E7 displayed on Lactobacillus casei induces E7-specific antitumor effects in C57/BL6 mice[J]. Int J Cancer, 2006, 119(7): 1702~1709.47 Qiao X Y, Li G W, Wang X Q, et al. Recombinant porcine rotavirus VP4 and VP4-LTB expressed in Lactobacillus casei induced mucosal and systemic antibody responses in mice[J]. BMC Microbiol, 2009, 9: 249.48 Ramasamy R, Yasawardena S, Zomer A. Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunizations[J]. Vaccine, 2006, 24(18): 3900~3908.49 Ribeiro L A, Azevedo V, Le Loir Y, et al. Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: A first step towards food-grade live vaccines against Brucellosis[J]. Appl Environ Microbiol, 2002, 68(2): 910~916.50 Sim A C N, Lin W W, Tan G K X, et al. Induction of neutralizing antibodies against dengue virus type 2 upon mucosal administration of a recombinant Lactococcus lactis strain expressing envelope domain Ⅲ antigen[J]. Vaccine, 2008, 26(9): 1145~1154.51 Stephenson D P, Moore R J, Allison G E. Transformation of, and heterologous protein expression in, Lactobacillus agilis and Lactobacillus vaginalis isolates from the chicken gastrointestinal tract[J]. Appl Environ Microbiol, 2011, 77(1): 220~228.52 Taheri H, Moravej H, Tabandeh F, et al. Screening of lactic acid bacteria toward their selection as a source of chicken probiotic[J]. Poultry Sci, 2009a, 88: 1586~1593.53 Taheri H, Tabandeh F, Moravej H, et al. Potential probiotic of Lactobacillus johnsonii LT171 for chicken nutrition[J]. Afri J Biotechnol, 2009b, 8(21): 5838~5837.54 Villena J, Medina M, Vintini E, et al. Stimulation of respiratory immunity by oral administration of Lactococcus lactis[J]. Can J Microbiol, 2008, 54(8): 630~638.55 Wang Z S, Gao J K, Yu Q H, et al. Oral immunization with recombinant Lactococcus lactis expressing the hemagglutinin of the avian influenza virus induces mucosal and systemic immune responses[J]. Future Microbiol, 2012a, 7(8): 1003~1010.56 Wang Z S, Yu Q H, Gao J K, et al. Mucosal and systemic immune responses induced by recombinant Lactobacillus spp. expressing the hemagglutinin of the avian influenza virus H5N1[J]. Clin Vaccine Immunol, 2012b, 19(2): 174.57 Wells J M, Wilson P W, Norton P M, et al. Lactococcus lactis: High-level expression of tetanus toxin fragment C and protection against lethal challenge[J]. Mol Microbiol, 1993, 8(6): 1155~1162.58 Wu C Y, Yang G, Bermúdez-Humarán L G, et al. Immunomodulatory effects of IL-12 secreted by Lactococcus lactis on Th1/Th2 balance in ovalbumin (OVA)-induced asthma model mice[J]. Int Immunopharmacol, 2006, 6(4): 610~615.59 Xin K Q, Hoshino Y, Toda Y. Immunogenicity and protective efficacy of orally administered recombinant Lactococcus lactis expressing surface-bound HIV Env[J]. Immunol, 2003, 102(1): 223~228.60 Xu Y G, Li Y J. Construction of recombinant Lactobacillus casei efficiently surface displayed and secreted porcine parvovirus VP2 protein and comparison of the immune responses induced by oral immunization[J]. Immunol, 2007, 124(1): 68~75.61 Yang S, Li W, Challis J R, et al. Probiotic Lactobacillus rhamnosus GR-1 supernatant prevents lipopolysaccharide-induced preterm birth and reduces inflammation in pregnant CD-1 mice[J]. Am J Obstet Gynecol, 2014, 211(1):44.e1~44.e12.62 Zhang Y, Wang H N, Wang T, et al. Complete genome sequence and recombination analysis of infectious bronchitis virus attenuated vaccine strain H120[J]. Virus Genes, 2010, 41(3): 377~388. |