中国畜牧兽医

• 动物营养与饲料科学 • 上一篇    下一篇

转Bt基因糙米作为日粮原料对生长猪免疫功能的影响

曹正辉12,王占彬2,顾宪红1   

  1. 1.中国农业科学院北京畜牧兽医研究所,动物营养学国家重点试验室,北京  1001932.河南科技大学动物科技学院,河南洛阳  471003

  • 收稿日期:2014-01-13 出版日期:2014-06-20 发布日期:2014-07-24
  • 通讯作者: 顾宪红(1966—),女,江苏人,研究员,博士生导师,研究方向:畜禽应激、福利与健康养殖。E-mail: guxianhong@vip.sina.com
  • 作者简介:曹正辉(1987—),男,河南人,硕士生,研究方向:营养生态学。
  • 基金资助:

    转基因生物新品种培育重大专项课题(2012ZX08011001)。

Effect of Transgenic Bt Brown Rice as the Dietary Ingredients on Immunity in Growing Pigs

CAO Zheng-hui1,2,WANG Zhan-bin2,GU Xian-hong1   

  1. 1. State Key Laboratory of Animal NutritionInstitute of Animal SciencesChinese Academy of Agricultural SciencesBeijing 100193China2.College of Animal Science and TechnologyHenan University of Science and TechnologyLuoyang 471003China

  • Received:2014-01-13 Online:2014-06-20 Published:2014-07-24

摘要: 本试验旨在研究转苏云金芽孢杆菌(Bacillus thuringiensis,Bt)基因糙米作为日粮原料对生长猪免疫功能的影响。选用80日龄大白仔猪30头,随机分为2组,每组15个重复,每个重复1头猪。对照组饲喂含70%亲本非转基因糙米的日粮,试验组饲喂含70%转Bt基因糙米的日粮,试验期90 d。结果显示,与对照组相比,饲喂转Bt基因糙米的生长猪血清中IgA、IgG、IgM含量及补体C3和C4水平差异均不显著(P>0.05);试验组生长猪的肝脏、脾脏组织切片观察发现,其亚显微结构均无病理变化,与对照组相比无明显差异(P>0.05),且两组间的免疫器官指数也均无显著差异(P>0.05)。综上所述,在本试验条件下,转Bt基因糙米作为生长猪的日粮,未见对生长猪的免疫器官及其功能造成影响。

关键词: Bt; 免疫功能;

Abstract: The experiment aimed to study the effect of transgenic Bt brown rice as growing pig’s diet on immunity in growing pigs.30 Large White piglets were randomly allocated into 2 dietary treatments with 15 replicates per treatment.The control group diet consisted of basic diet and 70% non-transgenic Bt brown rice,and the test group consisted of basic diet and 70% transgenic Bt brown rice. This experiment lasted for 90 days.The results showed that effect of transgenic Bt brown rice on IgA,IgG,IgM contents and complements C3 and C4 levels in serum were no significant differences between the two groups (P>0.05).Submicrostructure of liver and spleen of growing pigs in treatment group had no pathological changes according to tissue slice observation of two organs and also had no significant difference compared with the control group (P>0.05).And there were no significant differences in immune organ index between the two groups (P>0.05).In conclusion,under this experimental condition,Bt brown rice as growing pig’s diet fed to growing pigs will not cause damage to immune organs and will not influence immune function.

Key words: Bt; immune function; pig