›› 2012, Vol. 39 ›› Issue (6): 196-199.

• 流行病防治 • 上一篇    下一篇

猪繁殖与呼吸综合征病毒变异株感染猪超微结构研究

孟帆1, 姚敬明1, 吴忻1, 韩一超1, 樊振华1, 范瑞文2, 王娟萍1, 候燕平2, 刘文俊1, 米瑞娟1   

  1. 1. 山西省农业科学院畜牧兽医研究所,山西太原 030032;
    2. 山西农业大学,山西太谷 030801
  • 收稿日期:2011-11-02 出版日期:2012-06-20 发布日期:2012-07-02
  • 通讯作者: 姚敬明(1957-),男,山西人,副研究员,主要从事畜禽传染病的研究。
  • 作者简介:孟帆(1980-),女,山西人,硕士,助理研究员,主要从事畜禽传染病的研究。
  • 基金资助:
    山西省科技攻关项目(20080311036-1)。

Ultrastructure Study of Swine Infected with Shanxi Variant Strain of Porcine Reproductive and Respiratory Syndrome Virus

MENG Fan1, YAO Jing-ming1, WU Xin1, HAN Yi-chao1, FAN Zhen-hua1, FAN Rui-wen2, WANG Juan-ping1, HOU Yan-ping2, LIU Wen-jun1, MI Rui-juan1   

  1. 1. Shanxi Institute of Animal Husbandry and Veterinary Medicine,Taiyuan 030032,China;
    2. Shanxi Agricultural University,Taigu 030801,China
  • Received:2011-11-02 Online:2012-06-20 Published:2012-07-02

摘要: 利用透射电镜对山西省PRRSV变异株感染猪的肺脏、脾脏、肝脏、肾脏、淋巴结等组织进行超微病理变化的观察。试验结果发现,肺脏、脾脏、肝脏、肾脏、淋巴结各组织细胞均被不同程度地感染,各种细胞器遭受普遍的膜结构损伤,而以线粒体和细胞核变化较为严重。本研究为阐明PRRSV变异株感染猪的致病机理提供了理论依据。

关键词: 猪繁殖与呼吸综合征病毒变异株; 超微结构;

Abstract: The ultra microstructure of lung, spleen, liver,lymph node and other tissues from pigs infected with Shanxi variant strain of PRRSV were observed by transmission electron microscopy (TEm). Results showed that the pulmonary macrophages, the hepatocytes and the lymphocytes in the lymph nodes and the spleen were infected to different degrees, where the membranous structures of organelles was generally damaged, furthermore, the damage of mitochondria and cell nucleus was especially serious. The study shed light on pathogenesis of the disease.

Key words: variant strain of porcine reproductive and respiratory syndrome virus (PRRSV); ultrastructure; swine

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