›› 2009, Vol. 36 ›› Issue (8): 103-107.

• 奶业专栏 • 上一篇    下一篇

牛乳中分泌型IgA的合成机理及提高技术

杨光,王加启,哈斯额尔敦,赵圣国,刘开朗,卜登攀   

  1. (中国农业科学院北京畜牧兽医研究所 动物营养学国家重点实验室, 北京 100193)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-08-20 发布日期:2009-08-20
  • 通讯作者: 王加启

Secretion Mechanism and Improvement Technology of sIgA in Milk

YANG Guang,WANG Jia-qi,Khas-Erdene,ZHAO Sheng-guo,LIU Kai-lang,BU Deng-pan   

  1. (State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agriculture Sciences,Beijing 100193,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-08-20 Published:2009-08-20
  • Contact: WANG Jia-qi

摘要: 分泌型IgA(sIgA)是介导黏膜免疫的主要免疫球蛋白,它的诸多理化特性保证了其黏膜免疫作用的发挥;牛奶中sIgA的合成与分泌是生物进化中黏膜免疫的附属产品,是为子代提供黏膜被动免疫的途径;作者综述了sIgA的功能及牛乳中sIgA的产生机理;并总结了通过免疫乳生产来提高乳中sIgA浓度的几种方法,为今后高滴度sIgA免疫乳生产提供一定的参考。

关键词: 牛奶; sIgA; 黏膜免疫; 免疫乳

Abstract: sIgA is a primary immunoglobulin mediating mucosa immunity.Some physics and chemistry characteristics enable sIgA to lead mucosa immunity.Synthesis and secretion of sIgA in milk is accessorial production of mucosa immunity,which comes into being in evolution for offer passiveness immunity of mucosa for offspring.This article summarize function and synthesis mechanism of sIgA in milk.Some techniques to increase the content of sIgA in milk are introduced.Thus some references were offered for production of immune milk with high-titer sIgA in future.

Key words: milk; sIgA; mucosa immunity; immune milk

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