《中国畜牧兽医》 ›› 2017, Vol. 44 ›› Issue (3): 659-666.doi: 10.16431/j.cnki.1671-7236.2017.03.006

• 生物技术 • 上一篇    下一篇

宏基因组技术在鸡肠道微生物中应用的研究进展

杨天龙1, 刘旭川2, 廖奇1, 王淑玲1, 张春勇1,2, 葛长荣1, 冷静1,2   

  1. 1. 云南省动物营养与饲料科学重点实验室, 昆明 650201;
    2. 云南农业大学动物科学技术学院, 昆明 650201
  • 收稿日期:2016-09-01 出版日期:2017-03-20 发布日期:2017-03-21
  • 通讯作者: 葛长荣, 冷静 E-mail:gcrzal@126.com;Lenrui-1997@sohu.com
  • 作者简介:杨天龙(1993-),男,贵州天柱人,硕士生,研究方向:动物肠道微生态,E-mail:138887945@qq.com
  • 基金资助:

    国家自然科学基金项目(31672452);云南省自然科学基金重点项目(2014FA033);云南省中青年学术和技术带头人后备人才项目(2011HB025)

Application Advances of Metagenome Technology in Intestinal Microorganisms of Chicken

YANG Tian-long1, LIU Xu-chuan2, LIAO Qi1, WANG Shu-ling1, ZHANG Chun-yong1,2, GE Chang-rong1, LENG Jing1,2   

  1. 1. Yunnan Provincial Key Laboratory of Animal Nutrition and Feed Science, Kunming 650201, China;
    2. College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China
  • Received:2016-09-01 Online:2017-03-20 Published:2017-03-21

摘要:

鸡肠道中生存着丰富的微生物,这些微生物在宿主的营养代谢与免疫方面有重要作用。高通量测序技术的发展为肠道微生物的研究提供了新的思路,文章简要介绍了宏基因组学,阐述肠道微生物结构变化对宿主的影响及不同饲养条件、宿主生理特征改变对肠道微生的影响,并重点从宏基因组的层面透析鸡肠道微生物菌落结构、营养代谢特征、免疫功能与鸡的健康生长之间的关联性,以期为鸡肠道微生物的研究提供思路。

关键词: 鸡; 肠道微生物; 宏基因组; 营养代谢; 免疫功能

Abstract:

There are abundant microorganisms in the gastrointestinal tract of chicken, which play important roles in the metabolism and immunity of the host. The development of high-throughput sequencing technology for intestinal microbial research provides a new way of thinking. The article elaborates that metagenomics and effects of changes in intestinal microbial structure on the host and different feeding conditions, host physiological characteristics effect on intestinal microbial. This article focuses on the analysis of correlation between the intestinal microbial colony structure and characteristics of nutrient metabolism, immune function, and healthy growth of chicken on the level of metagenomics, and we hope to provide ideas for the study of intestinal microbial.

Key words: chicken; intestinal microorganisms; metagenomics; nutrient metabolism; immune fouction

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