肉鸡日粮中1α-羟基维生素D3与25-羟基维生素D3生物学效价比较研究

doi:10.16431/j.cnki.1671-7236.2015.12.020

›› 2015, Vol. 42 ›› Issue (12): 3246-3252.doi: 10.16431/j.cnki.1671-7236.2015.12.020

肉鸡日粮中1α-羟基维生素D₃与25-羟基维生素D₃生物学效价比较研究

韩进诚¹, 王建国^1,2, 陈冠华^1,2, 张金龙^1,2, 瞿红侠¹, 张进良¹, 席丽¹, 闫永峰¹

1. 商丘师范学院生命科学学院, 商丘 476000;
2. 河南农业大学牧医工程学院, 郑州 450002

收稿日期:2015-06-29 出版日期:2015-12-20 发布日期:2015-12-30
通讯作者: 闫永峰 E-mail:yanyf01@sina.com
作者简介:韩进诚(1977-),男,河北沧州人,副教授,研究方向:家禽营养与饲料科学,E-mail:j.c.han@hotmail.com
基金资助:
国家自然科学基金项目(31101732);河南省创新型科技人才队伍建设工程项目

Study on Relative Bioavailability of 1α-Hydroxycholecalciferol to 25-Hydroxycholecalciferol in Broiler Chickens

HAN Jin-cheng¹, WANG Jian-guo^1,2, CHEN Guan-hua^1,2, ZHANG Jin-long^1,2, QU Hong-xia¹, ZHANG Jin-liang¹, XI Li¹, YAN Yong-feng¹

1. College of Life Science, Shangqiu Normal University, Shangqiu 476000, China;
2. College of Animal Husbandry and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China

Received:2015-06-29 Online:2015-12-20 Published:2015-12-30

摘要/Abstract

摘要： 本试验比较了肉鸡日粮中1α-羟基维生素D₃(1α-OH-D₃)与25-羟基维生素D₃(25-OH-D₃)生物学效价。将300只1日龄罗斯308肉鸡公雏随机分为6个处理,每个处理5个重复,每个重复10只鸡。设计6种日粮,即在相同的基础日粮中分别添加2.5、5.0和10.0 μg/kg 25-OH-D₃和1.25、2.5和5.0 μg/kg 1α-OH-D₃,斜率比法测定1α-OH-D₃与25-OH-D₃的相对生物学效价。结果显示,日粮中添加1α-OH-D₃和25-OH-D₃可改善肉鸡平均体增重、料重比及血浆磷浓度,显著增加胫骨和股骨重量、长度和灰分重量(P< 0.05),而对骨骼钙和磷含量无显著影响(P >0.05)。以1~42日龄肉鸡平均体增重、料重比和血浆磷浓度评价,1α-OH-D₃生物学效价分别是25-OH-D₃的2.16、2.56和2.77倍;以42日龄肉鸡胫骨重量、长度、宽度和灰分重量评价,1α-OH-D₃生物学效价是25-OH-D₃的1.80、1.88、2.42和2.04倍;以42日龄肉鸡股骨重量、长度和灰分重量评价,1α-OH-D₃生物学效价是25-OH-D₃的1.89、1.98和2.18倍。试验表明,以1~42日龄肉鸡生长性能和骨骼矿化指标评价,1α-OH-D₃生物学效价约为25-OH-D₃的2.17倍。

关键词: 1α-羟基维生素D₃; 25-羟基维生素D₃; 生物学效价; 生长性能; 骨骼矿化; 肉鸡

Abstract: The study was conducted to determine the relative bioavailability (RBV) of 1α-hydroxycholecalciferol (1α-OH-D₃) to 25-hydroxycholecalciferol (25-OH-D₃) in Ross 308 broiler chickens from 1 to 42 days of age.300 one-day-old Ross 308 broilers were randomly assigned into 6 groups with 5 replicates per group and 10 chicks per replicate.The six groups were fed with basal diets in which 2.5,5.0,10.0 μg/kg 25-OH-D₃ and 1.25,2.5,5.0 μg/kg 1α-OH-D₃ were added,respectively.The RBV of 1α-OH-D₃ to 25-OH-D₃ was determined by the slope ratio method.The results showed that average body weight gain (ABWG),feed to gain ratio (F/G),plasma phosphorus (P) were improved with the 1α-OH-D₃ and 25-OH-D₃ addition and the tibia and femur weight,length,and ash weight were linearly increased with the levels of 1α-OH-D₃ or 25-OH-D₃ increasing (P< 0.05).Using ABWG,F/G,and plasma P as the criteria,RBV of 1α-OH-D₃ to 25-OH-D₃ were 2.16,2.56,and 2.77.Using tibia weight,length,width,and ash weight as the criteria,RBV of 1α-OH-D₃ to 25-OH-D₃ were 1.80,1.88,2.42,and 2.04.Using femur weight,length,and ash weight as the criteria,RBV of 1α-OH-D₃ to 25-OH-D₃ were 1.89,1.98,and 2.18.These results indicated that the activity of 1α-OH-D₃ was approximately 2.17 times higher than that of 25-OH-D₃in promoting growth performance and bone mineralization in broiler chickens from 1 to 42 days of age.

Key words: 1α-OH-D₃; 25-OH-D₃; bioavailability; growth performance; bone mineralization; broiler chick

中图分类号:

S831.5

韩进诚, 王建国, 陈冠华, 张金龙, 瞿红侠, 张进良, 席丽, 闫永峰. 肉鸡日粮中1α-羟基维生素D₃与25-羟基维生素D₃生物学效价比较研究[J]. , 2015, 42(12): 3246-3252.

HAN Jin-cheng, WANG Jian-guo, CHEN Guan-hua, ZHANG Jin-long, QU Hong-xia, ZHANG Jin-liang, XI Li, YAN Yong-feng. Study on Relative Bioavailability of 1α-Hydroxycholecalciferol to 25-Hydroxycholecalciferol in Broiler Chickens[J]. , 2015, 42(12): 3246-3252.

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肉鸡日粮中1α-羟基维生素D₃与25-羟基维生素D₃生物学效价比较研究

Study on Relative Bioavailability of 1α-Hydroxycholecalciferol to 25-Hydroxycholecalciferol in Broiler Chickens

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