霉菌毒素降解剂的研究进展

Abstract

Abstract: Mycotoxin was widely existed which done a serious threat to animal and human health，and it could be degraded by the mycotoxin degradation agents and reduced its toxicity which done damage to animals and humans，the degradation agents of mycotoxin were deeply studied at the moment.This article summarized from the dangers of mycotoxin，the classification degradation agents of mycotoxin，the degradation of mycotoxin applied in feed and provide relevant informations for the research of the mycotoxin.

Key words: mycotoxin; degradation agent; toxicity

QIAO Xia，DU Jun，ZHOU Xue-zhang. Research Progress on Degradation of Mycotoxins[J]. .

References

1 王金勇，刘颖莉，关舒.2012年中国饲料和原料霉菌毒素检测报告［J］.中国畜牧杂志，2013，49(4)：29～34.
2 王留，赵香菊.霉菌毒素降解剂对保育猪生长性能和抗氧化功能的影响［J］.养猪，2013，1：11～12.
3 计成，马秋刚，赵丽红，等.分泌霉菌毒素降解酶菌的筛选与解毒作用的研究［A］.第三届全国酶制剂在饲料工业中应用学术与技术研讨会［C］.2009.
4 邓友田.玉米赤霉烯酮毒性机理研究进展［J］.动物医学进展，2007，28（2）：89～92.
5 史莹华.蒙脱石纳米复合物吸附猪日粮中黄曲霉毒素B₁效果的研究［J］.动物营养学报，2007，19(6)：742～747.
6 龙淼，臧健，李鹏，等.黏膜乳杆菌清除液体中玉米赤霉烯酮能力的研究［J］.中国兽医学报，2013，3：458～461.
7 刘玉霞.玉米赤霉烯酮降解菌的筛选、鉴定及脱毒条件研究［D］.广州：华南理工大学，2011.
8 吕武兴，汪前红，贺建华，等.黄曲霉毒素与吸附剂对肉鸭生长及禽流感疫苗免疫的影响［J］.动物营养学报，2010，22(2)：431～436.
9 张保全，朱年华.芽孢杆菌在畜牧业中应用的研究进展［J］.江西畜牧兽医杂志，2007，1：2～3.
10 肖湘，李文平.霉菌毒素的毒性作用及对畜禽养殖业的危害研究进展［J］.湖南饲料，2012，1：25～27.
11 陈静，刘乃芝，武香玉，等.芽孢杆菌去除玉米赤霉烯酮的研究［A］.2012首届饲料脱霉技术研讨会暨霉菌毒素吸附剂大会论文集［C］.2012.
12 郑春芳，于桂阳.枯草芽孢杆菌对肉鸡生产性能的影响［J］.家禽科学，2011，4：38～40.
13 侯然然，张敏红.霉菌毒素对畜禽的危害及其防控方法的研究进展［J］.中国畜牧兽医，2007，34（1）：13～16.
14 常顺华.酯化葡甘露聚糖作为霉菌毒素吸附剂的研究［J］.饲料研究，2010，5：48～50.
15 程波财，史文婷，罗洁.玉米赤霉烯酮降解酶基因（ZEN-jjm）的克隆、表达及活性分析［J］.农业生物技术学报，2010，18(2)：225～230.
16 谭强来，徐锋，黎鹏.玉米赤霉烯酮降解酶毕赤酵母表达载体的构建及其表达［J］.中国微生态学杂志，2010，22(12)：1061～1064.
17 Benedetti R，Nazzi F，Locci R，et al.Degradation of fumonisin B₁ by a bacterial strain isolated from soil［J］.Biodegradtion，2006，17(1)：31～38.
18 Burgos-Hernández A，Price R L，Jorgensen-Kornman K，et al.Decontamination of aflatoxin₁-contaminated corn by ammonium persulphate during fermentation［J］.Journal of the Science of Food and Agriculture，2002，82(5)：546～552.
19 Cecchini F，Morassut M，Moruno E G，et al.Influence of yeast strain on ochratoxin A content during fermentation of white and red must［J］.Food Microbiology，2006，23(5)：411～417.
20 Cheng B，Wan C X，Yang S L，et al.Detoxification of deoxynivalenol by Bacillus strains［J］.Journal of Food Safety，2010，30(3)：599～614.
21 Cho K J，Kang J S，Cho W T，et al.In vitro degradation of zearalenone by Bacillus subtilis［J］.Biotechnology Letters，2010，32（12）：1921～1924.
22 Diaz D E，Hagler W M，Hopkins B A，et al.Aflatoxin binders Ⅰ：In vitro binding assay for aflatoxin B₁ by several potential sequestering agents［J］.Mycopathologia，2003，156(3)：223～226.
23 Etienne M，Dourmad J Y.Effects of zearalenone or glucosinolates in the diet on reproduction in sows：A review［J］.Livestock Production Science，1994，40(2)：99～113.
24 Freitas-Silva O，Venancio A.Ozone applications to prevent and degrade mycotoxins：A review［J］.Drug Metabolism Reviews，2010，42(4)：612～620.
25 Fink-Gremmels J，Malekinejad H.Clinical effects and biochemical mechanisms associated with exposure to the mycoestrogen zearlenone［J］.Animal Feed Science and Technology，2007，137：326～341.
26 Garda-Buffon J，Badiale-Furlong E.Kinetics of deoxynivalenol degradation by Aspergillus oryzae and Rhizopus oryzae in submerged fermentation［J］.Journal of the Brazilian Chemical Society，2010，21(4)：710～714.
27 Guan S，Ji C，Zhou T，et al.Aflatoxin B₁ degradation by Stenotrphomonas maltophilia and other microbes selected using coumarin medium［J］.International Journal of Molecular Sciences，2008，9(8)：1489～1503.
28 Hernandez-Mendoza A，Garcia H S，Steele J L.Screening of Lactobacillus casei strains for their ability to bind aflatoxin B₁［J］.Food and Chemical Toxicology，2009，47(6)：1064～1068.
29 Hormisch D，Brost I，Kohring G W，et al.Mycobacterium fluoranthenivorans sp. nov.，a fluoranthene and aflatoxin B₁ degrading bacterium from contaminated soil of a former coal gas plant［J］.Systematic and Applied Microbiology，2004，27(6)：653～660.
30 Ikunaga Y，Sato I，Grond S，et al.Nocardioides sp. strain WSN05-2，isolated from a wheat field，degrades deoxynivalenol，producing the novel intermediate 3-epi-deoxynivalenol［J］.Applied Microbiology and Biotechnology，2011，89(2)：419～427.
31 Jindal N，Mahipal S K，Mahajan N K.Toxicity of aflatoxin B₁ in broiler chicks and its reduction by activated charcoal［J］.Research in Veterinary Science，1994，56(1)：37～40.
32 Khatibi P A，Montanti J，Nghiem N P，et al.Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley-derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases［J］.Biotechnology for Biofuels，2011，4：26～38.
33 Kubena L F，Harvey R B，Buckley S A，et al.Effects of long-term feeding of diets containing moniliformin，supplid by Fusarium fujikuroi culture material，and fumonisin，supplied by Fusarium moniliforme culture material，to laying hens［J］.Poultry Science，1999，78(11)：1499～1505.
34 Lawlor P G，Lynch P B.Mycotoxin management［J］.African Farming and Food Processing，2005，46：12～13.
35 Li X Z，Zhu C，Zhou T，et al.Efficacy of detoxification of deoxynivalenol contaminated corn by Bacillus sp. LS100 in reducing the adverse effects of the mycotoxin on swine growth performance［J］.Food Additives and Contaminants：Part A，2011，28(7)：894～901.
36 Pang V F，Pan C Y.The cytotoxic effects of aflatoxin B₁ on swine lymphocytes in vitro［J］.Journal of the Chinese Society of Veterinary Sicence，1994，20（4）：289～301.
37 Paterson R R M，Lima N.Molecular，clinical and environmental toxicology［M］.Basel：Birkhuser Basel，2010.
38 Pestka J J.Deoxynivalenol：Toxicity，mechanisms and animal health risks［J］.Animal Feed Science and Technology，2007，137：283～298.
39 Petchkongkaew A，Taillandier P，Gasaluck P，et al.Isolation of Bacillus spp. from Thai fermented soybean(Thua-nao)：Screening for aflatoxin B₁ and ochratoxin A detoxification［J］.Journal of Applied Microbiology，2008，104(5)：1495～1502.
40 Tinyiro S E，Wokadala C，Xu D，et al.Adsorption and degradation of zearalenone by Bacillus strains［J］.Folia Microbiologica，2011a，56(4)：321～327.
41 Tinyiro S E，Yao W R，Sun X L，et al.Scavenging of zearalenone by Bacillus strains-in vitro［J］.Research Journal of Microbiology，2011b，6（3）：304～309.
42 Thieu N Q，Ogle B，Pettersson H.Efficacy of bentonite clay in ameliorating aflatoxicosis in piglets fed aflatoxin contaminated diets［J］.Tropical Animal Health and Production，2008，40(8)：649～656.
43 Var I，Kabak B，Erginkaya Z.Reduction in ochratoxin A levels in white wine，following treatment with activated carbon and sodium bentonite［J］.Food Control，2008，19（6）：592～598.
44 Yu H，Zhou T，Gong J H，et al.Isolation of deoxynivalenol-transforming bacteria from the chicken intestines using the approach of PCR-DGGE guided microbial selection［J］.BMC Microbiology，2010，10(1)：182.
45 Yu Y S，Qiu L P，Wu H，et al.Degradation of zearalenone by the extracellular extracts of Acinetobacter sp. SM04 liquid cultures［J］.Biodegradation，2011，22（3）：613～622.
46 Zaki M M，El-Midany S A，Shaheen H M，et al.Mycotoxins in animals: Occurrence， effects， prevention and management［J］.Journal of Toxicology and Environmental Health Sciences，2012，4（1)：13～28.

[1]	GUO Hongwei, CAI Yongchao, FAN Chunguang, HAO Kaixuan, CHANG Juan, WANG Ping, LIU Chaoqi, YIN Qingqiang. Effect of Compound Biological Detoxifier on Aflatoxin B₁ Degradation Rate Under Artificial Gastrointestinal Fluid Condition [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(4): 1395-1403.
[2]	TANG Qingfeng, LI Ling, HUANG Jiaxiang, FANG Wenyuan, NONG Haoru, TANG Yan, LU Chengwei, WEI Panqiu, FENG Ling. Survey on Mycotoxin Contamination of Buffalo Milk in Different Seasons Under Different Feeding Modes in Guangxi [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3665-3675.
[3]	ZHANG Xinxin, ZHANG Fujin, ZHANG Yao, GUO Zhigang, SUN Lin, LIU Guanghua, SHA Na. Analysis of Mycotoxin Contamination and Animal Health Risk Assessment in Silage Corn of China [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(12): 4451-4459.
[4]	HUANG Ke, WEN Xiaolu, WANG Li, JIANG Zongyong. Progress Research on the Hazard of Mycotoxins to Livestock and Poultry and the Methods of Reduction [J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(9): 2600-2607.
[5]	ZHANG Liyun, WANG Yanxin, WANG Yuke, OU Yahong, PENG Dapeng, WANG Xu, WANG Yulian, PAN Yuanhu, XIE Shuyu, CHEN Dongmei, HUANG Lingli, TAO Yanfei. Research Progress on Electrochemical Biosensors in Detection of Mycotoxins [J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(9): 2769-2777.
[6]	FAN Cai-yun, SU Di, LI Xiao-jiao, HUANG Shuai, ZHANG Yang-dong, ZHENG Nan, LIU Guang-lei, LIU Zhen, CHENG Jian-bo. Effects of Aflatoxin B₁ Individual,Binary or Tertiary Mixed with Ochratoxin A and Zearalenone on Intestinal Microorganism of Dairy Goat [J]. , 2017, 44(12): 3418-3425.
[7]	LIU Ning, YANG Zai-bin, YANG Wei-ren, JIANG Shu-zhen, ZHANG Gui-guo, YANG Ling, NIU Qun-sheng. Effects of Naturally Contaminated Corn and Corn Gluten Meal on Growth Performance, Apparent Digestibility and Serum Enzymes of Piglets [J]. , 2015, 42(3): 583-588.
[8]	FANG Si-min，BAI Fan，BAI Xue，GUO Chun-hua，ZHANG Zheng-fan，PENG Zhong-li. Research Progress on Detection Method，Hazard and Residual of Mycotoxins in Laying Hens [J]. , 2014, 41(6): 103-107.
[9]	DONG Shuang, HE Jian-bin, GUAN Xin, LONG Miao. Application of Flow Cytometry to Study Mycotoxins [J]. , 2014, 41(12): 258-262.
[10]	LIU Guo-rong, LIU Wen-qiang, LIU Fang-fang, LIU Hao. Epidemiological and Etiological Analysis of Chicken Infectious Proventriculitis [J]. , 2014, 41(10): 257-260.
[11]	ZHENG Nan, LI Song-li, XU Xiao-min, WANG Jia-qi. Risk Ranking of Mycotoxin in Milk in China [J]. , 2013, 40(S1): 9-11.
[12]	XIE Xiao-peng, YI Wei, ZHUANG Zhi-ming, ZHENG Jiao-que, ZOU Liu, XU Xi, PENG Meng-hua. Mycotoxins in Feed and its Prevention Measures [J]. , 2013, (5): 101-106.
[13]	ZHENG Nan;WANG Jia-qi;;HAN Rong-wei;XU Xiao-min;;ZHEN Yun-peng;;QU Xue-yin;;ZHAO Lian-sheng. Toxicity of Mycotoxins in Milk: A Review [J]. , 2012, 39(3): 10-13.
[14]	ZHENG Nan;WANG Jia-qi;;HAN Rong-wei;XU Xiao-min;;ZHEN Yun-peng;;QU Xue-yin;;ZHAO Lian-sheng. Main Risk Factor Analysis for Milk Quality and Safety Ⅱ.Mycotoxins [J]. , 2012, 39(3): 1-9.
[15]	ZHENG Nan;WANG Jia-qi;;HAN Rong-wei;XU Xiao-min;;ZHEN Yun-peng;;QU Xue-yin;;ZHAO Lian-sheng. Determination of Mycotoxins in Milk: A Review [J]. , 2012, 39(3): 14-18.

Research Progress on Degradation of Mycotoxins

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments