Abstract: A total of 214 fecal samples were collected and examined for intestinal Klebsiella. 88 strains of Klebsiella were isolated and identified by a series of tests, including isolation of bacteria, biochemical tests, etc. The separation rate was 41.12%. According to the clinical and laboratory standards institute (CLSI), antimicrobial susceptibility test, against 22 kinds of common antibiotics and other antibiotics, was carried out for the 88 strains of Klebsiella. Our results indicated that the 88 strains of Klebsiella showed varying degrees of drug resistance. They were of the highest resistance to carbenicillin (drug resistance rate was 95.45%). They had the highest sensitivity to amikacin (sensitivity rate was 77.27%).The phenomenon of multiple drug resistance occurred in all strains of Klebsiella. 64 of them were indentified to be resistant to 8 to 15 kinds of antibiotics,63 of them were resistant to more than ten kinds of antibiotics. On the other hand, the differences of drug resistance rates of Klebsiella against 22 kinds of common antibiotics and other antibiotics in four zoological gardens were considered. There was no significant difference of drug resistance rates of Klebsiella collected in CQ and BJ(P>0.05). The same thing occurred in SHW and SHZ, the strains of Klebsiella collected from the two zoological gardens performed the similar drug resistance rates. However, the drug resistance rates of Klebsiella in both SHW and SHZ extremly significantly differed from either BJ or CQ(P<0.01).

Key words: zoogical garden; non-human primates; Klebsiella; biochemistry test; antimicrobial susceptibility test