›› 2013, Vol. 40 ›› Issue (12): 116-120.

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Research Progress on the Milk Fat Synthesis Signal Transduction Pathway of FABP3

LIANG Meng-yao, GAO Xue-jun, LI Qing-zhang, HOU Xiao-ming   

  1. Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin 150030, China
  • Received:2013-05-28 Online:2013-12-20 Published:2014-02-11

Abstract: Fatty acid binding protein 3(FABP3) is a member of the fatty acid binding protein family and widely present in the myocardium, skeletal muscle and lactating breast in which tissues fatty acids are highly in demand. It is involved in transient storage and transportation of intracellular fatty acids. Into the mitochondrial energy metabolism system, fatty acid is oxidized and decomposed and produces ATP and provides energy for organisms. It combines with fatty acids to form intracellular and extracellular concentration differences and promotes the cellular uptake of fatty acids. This paper mainly introduces gene and protein structure, biological function and clinical application of FABP3 and reviews research progress of FABP3 in the milk fat synthesis signal transduction pathway.

Key words: FABP3; biological function; clinical application; milk fat; signal transduction pathway

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