激素对奶牛乳腺上皮细胞乳脂肪合成的调控作用

doi:10.16431/j.cnki.1671-7236.2021.08.011

Abstract

Abstract: Milk fat is a high quality natural fat which can provide nutrition and energy for human.Among all kinds of dietary fat and oil, it is the easiest to be digested and absorbed.Milk fat is a kind of lipid substance formed by esterification of de novo synthesis or exogenous intake of fatty acid and glycerol in the mammary gland, its content is related to the quality of milk and the processing characteristics of dairy products.During the lactation cycle of dairy cows, the lactation function of mammary gland is affected by many factors, among which a variety of hormones secreted by the endocrine glands have positive regulatory effects on the synthesis of milk fat in bovine mammary epithelial cells.To sum up, the authors introduced the regulatory mechanism of hydrocortisone, prolactin, insulin and growth hormone on milk fat synthesis in bovine mammary epithelial cells, explaining its regulatory effect from the appropriate amount of hormone in milk fat synthesis and the effect of hormone on the morphology of milk fat globule.And from the key enzymes of milk fat synthesis and transcription factors, hormones on the expression of milk fat synthesis-related genes, the mechanism is explained in depth, aiming to provide reference for studying the regulation mechanism of lactation-related hormones on milk fat synthesis in dairy cows' mammary glands.

Key words: bovine mammary epithelial cells; milk fat; hydrocortisone; prolactin; insulin; growth hormone

CLC Number:

S823.9⁺1

CAO Yue, LI Dabiao. Regulatory Effects of Hormones on Milk Fat Synthesis in Bovine Mammary Epithelial Cells[J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(8): 2778-2786.

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Regulatory Effects of Hormones on Milk Fat Synthesis in Bovine Mammary Epithelial Cells

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