猪繁殖与呼吸综合征病毒细胞受体研究进展

Abstract

Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) enters the host cells via a mechanism of receptor-mediated endocytosis. The entry mechanism is mediated by attachment to one or more cellular receptors and/or coreceptor on the cell surface and internalization. This article mainly describes several receptors for PRRSV. As far, it is reported five receptors of PRRSV which are independent and associated, heparin sulphate (HS), sialoadhesin (Sn),vimentin, CD163 and non-muscle myosinⅡA. It plays a significant role for the mechanism of PRRSV infection or disease prevention and treatment by studying the function of cellular receptors of PRRSV.

Key words: porcine reproductive and respiratory syndrome virus; receptor; sialoadhesin; heparin sulfate; vimentin; CD163; non-muscle myosinⅡA

CLC Number:

S852.2

LI Hong, ZHOU En-min, YI Jian-zhong. Research Progress on Cellular Receptors of Porcine Reproductive and Respiratory Syndrome Virus[J]. , 2013, (7): 77-81.

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Research Progress on Cellular Receptors of Porcine Reproductive and Respiratory Syndrome Virus

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