1 马喜芝,蔡丽君,吴晓晖,等.利用GAL4-UAS系统在果蝇中过表达研究人类基因功能[J].生物化学与生物物理学报,2003,35(7):597~600. 2 王海,陆泉枝,连正兴,等.电穿孔导入绿色荧光蛋白基因于绵羊胎儿成纤维细胞研究[J].中国畜牧杂志,2004,40(2):5~8. 3 叶迅,陆琴,赵毅,等.嵌合型E1B 55-kDa蛋白缺陷型腺病毒载体治疗肿瘤的评价[J].生物化学与生物物理进展,2005,32(12):1156~1164. 4 李瑶,崔海信,刘琪,等.磁性纳米颗粒作为基因载体的研究发展概况[J].功能材料,2010,41:14~19. 5 张晓金,原续波,胡云霞,等.具有靶向抗癌功能的O-CMC磁性纳米载体系统的制备[J].高分子通报,2004,3:89~92. 6 周芬.Ik6基因在急性淋巴细胞白血病中的表达及其功能的初步研究.武汉:华中科技大学,2011. 7 段卫明.RbAP46基因转染白血病细胞系的实验研究.苏州:苏州大学,2003. 8 薛志刚,郑多,阮建明,等.硅纳米颗粒作为基因转染载体的研究[J].遗传学报,2003,30(7):606~610. 9 冀慧莹.靶向沉默PLCε联合藏花素抑制膀胱癌BIU-87细胞增殖作用及机制研究.重庆:重庆医科大学,2008. 10 Blease R,Culver K,Miller A,et al.Tlymphocyte directed gene therapy for ADA-SCID:Initial trial results after 4 years[J].J Dairy Sci,1995,270:475~480. 11 Baki D E,Ebru K,Cengiz B,et al.Reactive and functional polymers[J].J Dairy Sci,2002,50(3):225~232. 12 Bharali D J,Khalil M,Gurbuz M,et al.Nanoparticles and cancer therapy:Aconcise review with emphasis on dendrimers[J].Int J Nanomedicine,2009,11(4):1~7. 13 Chang Y,Chen D.Material with functional groups is commonly used in preparation of magnetic micnosphere[J].Journal of Colloid and Interface Science,2005,283:446~451. 14 Chen Y,Xue Z,Zheng D,et al.Sodium chloride modified silica nanoparticles as a non-viral vector with a high efficiency of DNA transfer into cells[J].Curr Gene Ther,2003,3(3):273~279. 15 David V,Schaffer J T,Koerber K.Molecular engineering of viral gene delivery vehicles[J].Annu Rev Biomed Eng,2008,10(2):169~194. 16 Flavia P,Francesco T,Tiziana P,et al. Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus,Ad5/F35[J].Clin Cancer Res,2006,12(11): 3495~3501. 17 Gao S, Chen J, Xu X,et al.Galactoylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting[J].Int J Pharm,2003,255(1~2):57~68. 18 Gao S,Chen J,Dong L,et al.Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector[J].Eur J Pharm Biopharm,2005,60(3):327~334. 19 Graham F L,Van Der Eb A J.A new technique for the assay of infectivity of human adenovirus 5 DNA[J].Virology,1973,52(2):456~467. 20 Iwasaki Y,Ueda M,Yamada T,et al.Gene therapy of liver tumors with human liver specific nanoparticles[J].Cancer Gene Ther,2007, 14(1):74~81. 21 Kone B C.Molecular approaches to renal physiology and therapeutics[J].Seminars Nephrol,1998,18(2):102~121. 22 Liu W G,Yao K D.DNA-polycation nanospheres as nonviral gene delivery vehicles[J].J Control Rel,2002,83:1~11. 23 Lu C R,Chen L,Dou C Q,et al. Arresten expressed in vivo suppresses the growth of SGC-7901 tumor xenografts in nude mice[J].Chinese Journal of Surgery,2005,43(21):1391~1394. 24 Newman C M H,Bettinger T.Gene therapy progress and prospects:Ultrasound for gene transfer[J].Gene Therapy,2007,14(6):465~475. 25 Pierre L,Sylvie F,Noufissa O,et al.Gene delivery systems:Bridging the gap between recombinant viruses and artificial vectors[J].Adv Drug Delve Rev,1998,30(1~3):5~11. 26 Recillas T F.Multiple strategies for gene transfer,expression,knockdown,and chromatin influence in mammalian cell lines and transgenic animals[J].Mol Biotechnol,2006,34(3):337~354. 27 Richardson S C,Kolbe H V,Duncan R.Potential of low molecular mass chitosan as a DNA delivery system:Biocompatibility,body distribution and ability to complex and protect DNA[J].Int J Pharm,1999,178:231~243. 28 Song E,Lee S K,Wang J,et al.RNA interference targeting Fas protects mice from fulminant hepatitis[J].Nat Med,2003,9:347. 29 Tan K,Cheang P,Ho I A,et al.Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen[J].Gene Therapy,2007,14(10):828~835. 30 Xiang G,Kim K,Liu D.Nonviral gene delivery: What we know and what is next[J].AAPS J,2007,9(1):92~104. 31 Yang N S,Sun W H.Gene gun and other nonviral approaches for cancer gene therapy[J].Nat Med,1995,1(5):481~483. |