非洲马瘟疫苗的研究进展

Abstract

Abstract: African horse sickness (AHS) is a non-contagious, insect-borne disease of equids, caused by African horse sickness viruses. This disease is included in the single Office International des Epizooties list of notifiable terrestrial animal diseases, and at present, is enzootic in such areas as sub-Saharan Africa. AHS is mainly transmitted by Culicoides midges, which grow and reproduce in the endemic areas, being responsible for the epidemiological status of this disease. The live attenuated vaccines and inactivated vaccines against AHS have been commercialized and been widely used. The new generation vaccines based on genetic engineering, such as subunit vaccines and viral vector vaccines, are being developed and will probably enter the vaccine marketplace in the future. In this review, we discussed the current status of vaccines against AHS in detail.

Key words: African horse sickness; African horse sickness virus; live attenuated vaccine; inactivated vaccine; DIVA strategy

CLC Number:

S816.79

HE Yu-qian, WU Hai-yan. Research Progress in Development of Vaccines against African Horse Sickness[J]. , 2012, 39(7): 209-213.

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Research Progress in Development of Vaccines against African Horse Sickness

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