牛支原体疫苗的研究进展

doi:10.16431/j.cnki.1671-7236.2018.03.026

Abstract

Abstract:

Mycoplasma bovis (M.bovis) is a pathogen that causes a variety of diseases in beef cattle and dairy cows around the world.Clinical symptoms include chronic pneumonia and polyarthritis syndrome (CPPS),bovine respiratory disease complex (BRD),mastitis and genital disorders.M.bovis can infect a variety of tissues and organs,and can also be isolated from healthy cattle.It is the major causative agent that threatens livestock production.Due to the resistance to antibiotic therapy,the best option of preventing and controlling the infection of M.bovis is to develop effective commercially available vaccines.The research on the vaccine of M.bovis has been going on for many years.Despite some problems,the M.bovis vaccines have made some good progress.In this paper,the advances on the research of attenuated vaccines,inactivated vaccines and subunit vaccines against M.bovis were summarized,and the optimization plan of vaccines design were discussed,which could provide reference for the rational design and development of effective M.bovis control techniques.

Key words: Mycoplasma bovis; attenuated vaccine; inactivated vaccine; subunit vaccine

CLC Number:

S858.23

JI Wenheng, WU Yaqin, ZHAI Xiaohui, CHU Yuefeng. Advances on the Research of Vaccine Against Mycoplasma bovis[J]. , 2018, 45(3): 763-769.

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Advances on the Research of Vaccine Against Mycoplasma bovis

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