Abstract: To study the distribution and localization of the gonadotropin receptor (FSHR,LHR) in the position of the female buffalo genital. The localization of FSHR and LHR in adult buffalo ovary,uterus and oviduct during the follicular phase and the luteal phase were determined by immunohistochemical SABC techniques.The results showed that FSHR/LHR immunoreactive substance was mainly distributed in the thecal cells and granulose cells in the ovary,the endometrial epithelial cells,glandular cells in uterus,the ciliated columnar epithelial cells in the oviduct. The expression of FSHR and LHR was dependent on the stage of the estrus cycle,with the estrus in which different,FSHR,LHR expression were also different,the expression of FSHR,LHR in ovarian are higher during the follicle phase than those during the luteal phase. the expression of FSHR in uterus was higher during the follicle phase than during the luteal phase,the expression of LHR in uterus was higher during the luteal phase than during the follicular phase. The expression of oviduct was no significant differences.

Key words: FSHR; LHR; buffalo; genital; immunohistochemistry