黄芪多糖佐剂对Ⅰ型鸭疫里氏杆菌灭活疫苗的作用研究

Abstract

Abstract: An inactivated astragalus polysaccharide (APS) adjuvant vaccine was developed with Riemerella anatipestifer (RA) serotype Ⅰ isolated from Wuhan in this research. Ducks were inoculated with optimal dosage (0.3 mL/duck) at the age of 5-day. The protection rates were 100%, 90%, 100%, 100% and 90% on the 3 rd, 7 th, 10 th, 14 th and 21 st day after vaccination, respectively. Immunodiffusion assay showed that the specific antibody could be found since 3 rd day post inoculation, and reached peak on 10 th day (P<0.01). These results suggested that this vaccine could against duck infectious serositis effectually.

Key words: Riemerella anatipestifer serotypeⅠ; duck infectious serositis; astragalus polysaccharide; inactivated vaccine

CLC Number:

S862.4⁺3

JIN Er-guang;CHEN Jie;QIAN Yun-guo;CHEN Cheng;ZENG Xin-hua;GONG Shi-yu;HUA Juan. Study on the Effect of Astragalus Polysaccharide Adjuvant to Inactivated Vaccine of Riemerella Anatipestifer SerotypeⅠ[J]. , 2009, 36(3): 151-152.

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Study on the Effect of Astragalus Polysaccharide Adjuvant to Inactivated Vaccine of Riemerella Anatipestifer SerotypeⅠ

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