Abstract: To provide the basis for the disease prevention,diagnosis and therapy, epidemiological investigation of canine parvovirus was carried out. 189 stool samples of dogs suffered from diarrhea, vomiting, blood feces and other signs were detected for antigen with canine parvovirus detection kit during 2008.And 16 samples of canine parvovirus-positive cases combined with fever, cough signs were detected for canine distemper virus at the same time. The cases of canine parvovirus-positive was 137. Dogs aged from 1 month to 15-years-old could be infected.There was a high incidence in 6-months-old and more young animals, accounting for 65.7%,little difference among four seasons during the year, slightly more cases in spring, accounting for 27.0%. Canine parvovirus and canine distemper virus were found at the same time in 12 cases, accounting for 8.8%. Three of four samples were appeared to be positive for canine parvovirus during the term of vaccination protection.Conclusions: ①Immunity has not yet been established,which is the main cause in puppies. ②Not in accordance with established procedures to strengthen the immunity of animals is the main cause in adult dogs. ③There are a few puppies co-infected with canine parvovirus and canine distemper virus. ④Aging animals are in low level on the immune response,which can lead to immune failure.

Key words: canine parvovirus; epidemic situation; cause