PCI-Ghrelin-28aa质粒微球对小鼠的促生长效应

Abstract

Abstract: Injectable sustained release PCI-Ghrelin-28aa were prepared by double emulsion-in liquid evaporation process, using biodegrable poly lactic acid as carrier. The result of transfection in vivo showed that after 25 days, accumulative increased body weights on the group injected with PCI-Ghrelin-28aa microspheres was higher than those group injected with naked plasmid(14.3%), saline(27.9%) respectively. In conclusion, PCI-Ghrelin-28aa microspheres have a controlled release effect and tendency to enhance absorb and expression of PCI-Ghrelin-28aa.

Key words: PLGA; Ghrelin; growth

CLC Number:

Q782

YANG Lianyu;GENG Chunyin;XIE Jinfang;LIU Jiajia;XU Yongping. Somatotropic Efficacies of PCI-Ghrelin-28aa Carried with PLGA Microspheres [J]. , 2007, 34(7): 26-28.

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Somatotropic Efficacies of PCI-Ghrelin-28aa Carried with PLGA Microspheres

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