阿魏酸对脂多糖应激的吉林白鹅生长性能和肠道抗氧化指标的影响

doi:10.16431/j.cnki.1671-7236.2024.02.009

Abstract

Abstract: 【Objective】 The aim of this study was to investigate the effects of ferulic acid (FA) on the growth performance, organ indexes, and intestinal anti-oxidant indicators of Jilin White geese induced by lipopolysaccharide (LPS), and provided a reference for alleviating oxidative stress in goose breeding.【Method】 A total of 120 healthy male Jilin White geese aged 7 days were randomly divided into 6 groups (5 replicates per group, 4 geese per replicate):Group K (blank control group), group L (LPS control group), and groups A, B, C, and D (supplemented with 60, 120, 180, and 240 mg/kg FA, respectively).On days 14, 17, and 20 of the formal experiment, the geese in groups L, A, B, C, and D were injected with 0.5 mg/kg LPS intraperitoneally, while the geese in group K was injected with an equal volume of saline.On day 21, 10 geese were randomly selected from each group for slaughter, and the hearts, livers, spleens, kidneys, bursa of Fabricius, and thymuses were removed and weighed to calculate the organ indexes.The duodenum, jejunum, and ileum were separated for determination of intestinal antioxidant indicators.【Result】 ① On the 1st to 14th day, compared with the group L, the final body weight (FB), average daily feed intake (ADFI), and average daily gain (ADG) in group C were significantly increased, while the feed-to-gain ratio (F/G) was significantly decreased (P＜0.05).Except for ADFI, which was significantly higher than that of group K, other indicators in Group C were not significantly different from Group K (P＞0.05).On the 15th to 21st day, compared with group L, FB, ADG, and ADFI in groups A, B, C, and D were significantly increased, while F/G was significantly decreased (P＜0.05), and some indicators showed no significant difference compared to group K (P＞0.05).On the 1st to 21st day, compared with the group L, the ADG and ADFI in groups B and C were significantly increased, while F/G was significantly decreased (P＜0.05), and there was no significant difference compared to group K (P＞0.05).②The thymus index in group D was significantly higher than that in groups L and K in organ indexes (P＜0.05).③ In the duodenum, the content of malondialdehyde (MDA) in groups A, C, and D were significantly lower than that in group L (P＜0.05), and there was no significant difference compared to group K (P＞0.05).④ In the jejunum, MDA content and glutathione peroxidase (GSH-Px) activity in group C were significantly higher than those in group L (P＜0.05), and there was no significant difference compared to group K (P＞0.05);The activity of catalase (CAT) in group C was significantly higher than that in groups L and K (P＜0.05). ⑤In the ileum, MDA content in groups B and C was significantly lower than that in group L, and GSH-Px activity in group C was significantly higher than that in group L (P＜0.05), and there was no significant difference compared to group K (P＞0.05).【Conclusion】 The addition of 180 mg/kg ferulic acid in the diet could promote the growth of geese and alleviate oxidative stress damage in various intestinal segments.

Key words: ferulic acid; Jilin White goose; lipopolysaccharide stress; growth performance; intestinal antioxidant capacity

CLC Number:

S835

LIU Yingkun, GUO Wei, FU Zengyu, SUN Meng, LI Haojia, ZHOU Haizhu. Effects of Ferulic Acid on Growth Performance and Intestinal Anti-oxidant Indicators of Jilin White Geese Under Lipopolysaccharide Stress[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(2): 521-529.

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Effects of Ferulic Acid on Growth Performance and Intestinal Anti-oxidant Indicators of Jilin White Geese Under Lipopolysaccharide Stress

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