China Animal Husbandry and Veterinary Medicine ›› 2025, Vol. 52 ›› Issue (2): 864-873.doi: 10.16431/j.cnki.1671-7236.2025.02.036

• Preventive Veterinary Medicine • Previous Articles    

Research Progress on Diagnosis and Control of Chinese Sacbrood Disease

LI Aifang1, WANG Qianfang2, WANG Zilong1, LI Yalan1, XU Peng1, FENG Shuying1   

  1. 1. School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China;
    2. College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China
  • Received:2024-06-15 Published:2025-01-24

Abstract: Chinese sacbrood disease (CSBD) is a viral disease caused by Chinese sacbrood virus (CSBV),which is seriously harmful to bee colonies,highly infectious,and the mortality rate is as high as 100%,which has caused huge economic losses to China’s beekeeping industry.Although a variety of methods and measures have been adopted in actual production to prevent and treat the disease,the effect is not good.The rapid development of detection technology for CSBV,especially the update of molecular biological detection methods,has greatly improved the accuracy and specificity of detection results.Egg yolk antibodies (EYA) have significant application effect in a variety of viral diseases,which has potential application and development value for the prevention and treatment of CSBD.The authors reviewd the latest research progress in the diagnosis,prevention and treatment of CSBD,and summarized the current application of EYA antibody drugs in the treatment of CSBD.In addition,on the basis of analyzing the advantages and disadvantages of EYA drugs,a variety of EYA synergistic strategies were proposed,and the research prospects against CSBV were looked forward from many aspects,such as the development of new antibody drugs,the identification of new traditional Chinese medicine monomers/formulations,and the development of nucleotide drugs,in order to provide reference for the prevention and control of viral diseases of apiculture.

Key words: Chinese sacbrood virus (CSBV); diagnosis; prevention and treatment; egg yolk antibodies (EYA)

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