不同组学视角分析中药抗病毒作用研究进展

doi:10.16431/j.cnki.1671-7236.2025.02.006

Abstract

Abstract: Viruses are one of the most important microorganisms causing diseases,which seriously endanger the health and life safety of human beings and animals.With the constant variation and recombination of viruses,such as Influenza virus,Severe acute respiratory syndrome coronavirus 2 and Porcine reproductive and respiratory syndrome virus,the protection provided by vaccines is limited.At the same time,the lack of effective antiviral drugs makes it difficult to treat viral infections.Therefore,it is an urgent need to find a new,safe and effective prevention and control methods to prevent viral infections.Traditional Chinese medicines have been widely used in antiviral research because of their safe composition,low resistance to drugs,and their ability to act on viruses in multiple ways and at multiple targets.Traditional Chinese medicine provides a rich base for antiviral drugs,but traditional experimental methods for antiviral drug development is time-consuming and heavy workload,the development of omics technology provides a new perspective for antiviral drug development,the use of omics data to analyze the relationship between drugs and diseases has become a powerful means of screening,evaluating the efficacy of drugs and discovering new drug targets.Therefore,the authors summarize and analyze the progress of transcriptomics,proteomics,metabolomics and multi-omics integration analysis in the antiviral research of traditional Chinese medicine,and analyze the application of traditional Chinese medicine in antiviral research through different omics perspectives,which not only contributes to an in-depth understanding of the antiviral mechanism of traditional Chinese medicine,but also provides a scientific basis for the research and development and optimization of antiviral drugs.

Key words: traditional Chinese medicine; antiviral effect; transcriptomics; proteomics; metabolomics; multi-omics integration analysis

CLC Number:

S853.74

LUO Qin, LIU Dingyu, LIU Baoling, QIAO Changhong, CHEN Xiangyu, HE Zhenwen, WANG Xiaohu, CHEN Jing, ZHANG Pian, HUANG Yuan, WANG Gang, LIU Hao, CAI Rujian. Research Progress on Antiviral Effect of Traditional Chinese Medicine Analyzed from Different Omics Perspectives[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(2): 554-561.

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Research Progress on Antiviral Effect of Traditional Chinese Medicine Analyzed from Different Omics Perspectives

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