非洲猪瘟病毒致病机制及防治策略研究进展

doi:10.16431/j.cnki.1671-7236.2024.07.029

Abstract

Abstract: African swine fever (ASF) is an acute,hemorrhagic and highly contagious disease,which has a huge negative impact on the world pig industry and food security.There are still no specific drugs and vaccines for the prevention and treatment.African swine fever virus (ASFV) is a large,complex double-stranded DNA virus,but the function of 80% of the encoded proteins is unknown.Therefore,its pathogenic mechanism and drug research status are of great significance for prevention and control. The author summarized the pathogen characteristics,transmission routes and clinical manifestations of ASFV.The latest progress of viral pathogenesis was reviewed from the aspects of virus invasion process,immune cell function changes and related pathway changes.The latest detection technology and vaccine progress of ASFV were introduced.This paper systematically summarized the latest research status of Chinese and Western medicine treatment,the future prospects of traditional Chinese medicine in the prevention and treatment of ASFV were prospected,and the key research directions and related problem solving strategies in the future were put forward,in order to provide reference and practical guidance for the treatment of ASF.

Key words: African swine fever virus (AFSV); pathogenic mechanism; preventive measures; traditional Chinese medicine

CLC Number:

S855.3

WANG Meile, YU Yangfan, XU Peng, CHEN Qing, AKILA·ANWAR, LI Shuxuan, YANG Songhua, YIN Sugai, FENG Shuying. Research Progress on the Pathogenic Mechanism and Prevention Strategy of African Swine Fever Virus[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(7): 3041-3055.

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Research Progress on the Pathogenic Mechanism and Prevention Strategy of African Swine Fever Virus

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