China Animal Husbandry and Veterinary Medicine ›› 2023, Vol. 50 ›› Issue (1): 390-397.doi: 10.16431/j.cnki.1671-7236.2023.01.039

• Basic Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Immune Adjuvant Effect and Related Mechanism of Active Ingredients of Traditional Chinese Medicine on Animal Vaccines

LIU Hongying1, WANG Jingyu3, CUI Zhenzhen1, MA Qingxia2, WANG Tingting2, LI Jianming1,4, SHI Kun1,4, GONG Qinglong2, DU Rui1,4, LENG Xue1,4   

  1. 1. College of Chinese Medicine Materials, Jilin Agricultural University, Changchun 130118, China;
    2. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China;
    3. Jilin Academy of Agricultural Sciences, Changchun 130118;
    4. Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China
  • Received:2022-06-17 Online:2023-01-05 Published:2023-01-04

Abstract: As an important part of vaccines, adjuvants have received extensive attention for their safety and their immune-enhancing effects on vaccines.There are many kinds of adjuvants for animal vaccines, including aluminum adjuvant, oil emulsion adjuvant and liposome adjuvant.Due to the limited adjuvants available and the increasing demand for vaccines, the search for safer and more effective vaccine adjuvants has become a new upsurge.Traditional Chinese medicine has the characteristics of easy access, low toxicity and strong immune activity.It has the potential to become a new vaccine adjuvant.This article reviewed the adjuvant activity of the active ingredients of traditional Chinese medicine, the immune regulatory effect and the mechanism of action after the combined vaccine, expounded on the possibility and research progress of the active ingredients of traditional Chinese medicine as adjuvants for animal vaccines, and provided a theoretical basis for the development of new adjuvants.

Key words: traditional Chinese medicine; animal vaccines; adjuvant; mechanism of action

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