China Animal Husbandry and Veterinary Medicine ›› 2023, Vol. 50 ›› Issue (12): 5123-5135.doi: 10.16431/j.cnki.1671-7236.2023.12.034

• Basic Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Drug Resistance, Detection Methods and Prevention and Control Technologies of Swine Salmonella

HE Zhenwen1,2, LIU Dingyu2,3, LIU Baoling2, CHEN Tianbao2, WANG Gang2, WANG Xiaohu2, LIU Wenjun1, CAI Rujian2   

  1. 1. College of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China;
    2. Scientific Observation and Experiment Station of Veterinary Drugs and Diagnostic Techniques of Guangdong Province of Ministry of Agriculture and Rural Affairs, Key Laboratory of Livestock Disease Prevention of Guangdong Province, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
    3. The Cooperative Innovation Center for Sustainable Pig Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430000, China
  • Received:2023-06-03 Online:2023-12-05 Published:2023-11-28
  • Contact: 广东省省级科技计划项目(2023B0202010014);广州市农村科技特派员项目(20212100015);2021年英德市科技计划项目 E-mail:466866569@qq.com

Abstract: Swine Salmonella is a zoonotic pathogen that can cause acute systemic infections in young pigs,seriously hindering the development of the breeding industry.Swine Salmonella can be transmitted to humans through the food chain,posing a potential threat to public health.Antibiotics are commonly used to control swine Salmonella in production,but the widespread use of antibiotics has led to the continuous enhancement of its resistance and the expansion of its resistance spectrum,increasing the difficulty of prevention and control.With the continuous development of bacteria detection technology and in-depth research on Salmonella,low-cost,simple and specific detection methods have been developed and applied,providing technical support for the detection of Salmonella.Vaccine immunization is one of the important means to prevent swine Salmonella.Currently,the vaccines on the market are mainly live attenuated vaccines,which have the advantages of good immunogenicity and durable protection,and inactivated vaccines and genetic engineering vaccines are also under development.In addition to antibiotics for the treatment and control of Salmonella,traditional Chinese medicine preparations and micro-ecological drugs also have good inhibitory effects on Salmonella,and are considered to be good substitute products with good development and application prospects.In this paper,the current situation of drug resistance of swine Salmonella was described,and the research progress of detection methods and control technologies of swine Salmonella was summarized,in order to provide theoretical basis and new ideas for the prevention and control of swine Salmonella.

Key words: swine Salmonella; drug resistance; detection methods; prevention and control technologies

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