黑水虻对猪禽肠道健康和肠道菌群影响的研究进展

doi:10.16431/j.cnki.1671-7236.2022.10.015

Abstract

Abstract: In recent years,the price of feed protein raw materials has continued to rise,and China is in short supply of feed protein raw materials and relies on imports for a long time.Therefore,finding and developing new protein sources has become a research hotspot to solve the shortage of feed protein raw materials.Hermetia illucens is a kind of saprophytic insect of diptera,Stratiomyidae family.It can transform organic waste into biological matter with high added value quickly,and has obvious advantages of low breeding cost,fast breeding speed and high output.It is rich in amino acids,antimicrobial peptides (AMPs),chitin and other bioactive substances,and its high proportion of protein and fat content lays a foundation for it to be a high-quality animal feed.A large number of studies have shown that Hermetia illucens partly replaces feed protein composition can effectively enhance animal immune and antioxidant capacity,at the same time through positive regulating intestinal beneficial microbial population and increase the way bacteria abundance,have the effect of improving animal intestinal health,as a kind of promising protein feed raw materials is expected to find a new breakthrough for animal husbandry and aquaculture.The authors have briefly described nutrition characteristic and main active ingredient of Hermetia illucens,systematically summarized the latest research progress on the effects of feeding Hermetia illucens on intestinal barrier,immune function and intestinal flora of pigs and poultry.The future research ideas and development direction of Hermetia illucens are prospected,in order to provide references for the further development and research of Hermetia illucens and its popularization and application in animal breeding production.

Key words: Hermetia illucens; intestinal health; intestinal flora; protein feed raw materials

CLC Number:

S816.48

ZHONG Chonghua, GUI Fuxing, CAO Liting, GUO Rongfu. Research Advances of Hermetia illucens on Intestinal Health and Microflora in Pigs and Poultry[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(10): 3829-3837.

References

[1] VAN RAAMSDONK L W D,VAN DER FELS-KLERX H J,DE JONG J.New feed ingredients:The insect opportunity[J].Food Additives & Contaminants,2017,34(8):1384-1397.
[2] HAWKEY K J,LOPEZ-VISO C,BRAMELD J M,et al.Insects:A potential source of protein and other nutrients for feed and food[J].Annual Review of Animal Biosciences,2021,9:333-354.
[3] JANTZEN DA SILVA LUCAS A,MENEGON DE OLIVEIRA L,DA ROCHA M,et al.Edible insects:An alternative of nutritional,functional and bioactive compounds[J].Food Chemistry,2020,311:126022.
[4] FENG Y,CHEN X,ZHAO M,et al.Edible insects in China:Utilization and prospects[J].Insect Science,2018,25(2):184-198.
[5] SHAH A A,TOTAKUL P,MATRA M,et al.Nutritional composition of various insects and potential uses as alternative protein sources in animal diets[J].Animal Bioscience,2022,35(2):317-331.
[6] KAWASAKI K,HASHIMOTO Y,HORI A,et al.Evaluation of black soldier fly (Hermetia illucens) larvae and pre-pupae raised on household organic waste,as potential ingredients for poultry feed[J].Animals: An Open Access Journal from MDPI,2019,9(3):98.
[7] CHU X,LI M,WANG G,et al.Evaluation of the low inclusion of full-fatted Hermetia illucens larvae meal for layer chickens:Growth performance,nutrient digestibility,and gut health[J].Frontiers in Veterinary Science,2020,7:585843.
[8] 王路逸,李泽轩,易犁,等.黑水虻对三种病原菌的杀灭作用研究[J].安全与环境工程,2022,29(1):199-206. WANG L Y,LI Z X,YI L,et al.Killing effect on three pathogenic bacteria by black soldier fly larvae[J].Safety and Environmental Engineering,2022,29(1):199-206.(in Chinese)
[9] BRUNO D,MONTALI A,MASTORE M,et al.Insights into the immune response of the black soldier fly larvae to bacteria[J].Frontiers in Immunology,2021,12:745160.
[10] VAN HUIS A.Potential of insects as food and feed in assuring food security[J].Annual Review of Entomology,2013,58:563-583.
[11] LI Q,ZHENG L,QIU N,et al.Bioconversion of dairy manure by black soldier fly (Diptera:Stratiomyidae) for biodiesel and sugar production[J].Waste Management,2011,31(6):1316-1320.
[12] ZHOU F,TOMBERLIN J K,ZHENG L,et al.Developmental and waste reduction plasticity of three black soldier fly strains (Diptera:Stratiomyidae) raised on different livestock manures[J].Journal of Medical Entomology,2013,50(6):1224-1230.
[13] LIU X,CHEN X,WANG H,et al.Dynamic changes of nutrient composition throughout the entire life cycle of black soldier fly[J].PLoS One,2017,12(8):e182601.
[14] WANG Y S,SHELOMI M.Review of black soldier fly (Hermetia illucens) as animal feed and human food[J].Foods,2017,6(10):91.
[15] YU M,LI Z,CHEN W,et al.Hermetia illucens larvae as a fishmeal replacement alters intestinal specific bacterial populations and immune homeostasis in weanling piglets[J].Journal of Animal Science,2020,98(3):1-13.
[16] DO S,KOUTSOS L,UTTERBACK P L,et al.Nutrient and AA digestibility of black soldier fly larvae differing in age using the precision-fed cecectomized rooster assay1[J].Journal of Animal Science,2020,98(1):skz363.
[17] BARROSO F G,DE HARO C,SNCHEZ-MUROS M J,et al.The potential of various insect species for use as food for fish[J].Aquaculture,2014,422-423:193-201.
[18] ABD EL-HACK M,SHAFI M,ALGHAMDI W,et al.Black soldier fly (Hermetia illucens) meal as a promising feed ingredient for poultry:A comprehensive review[J].Agriculture,2020,10(8):339.
[19] DICK K B B,DICKE M,LOON J J A.Nutritional value of the black soldier fly (Hermetia illucens L.) and its suitability as animal feed——A review[J].Journal of Insects as Food and Feed,2017,3(2):105-120.
[20] MAKKAR H P S,TRAN G,HEUZ V,et al.State-of-the-art on use of insects as animal feed[J].Animal Feed Science and Technology,2014,197:1-33.
[21] ELHAG O,ZHOU D,SONG Q,et al.Screening,expression,purification and functional characterization of novel antimicrobial peptide genes from Hermetia illucens (L.) [J].PLoS One,2017,12(1):e169582.
[22] XIA J,GE C,YAO H.Antimicrobial peptides from black soldier fly (Hermetia illucens) as potential antimicrobial factors representing an alternative to antibiotics in livestock farming[J].Animals,2021,11(7):1937.
[23] 王青,陈俊,李潇潇,等.黑水虻抗菌肽的研究进展[J].天然产物研究与开发,2021,33(11):1982-1989. WANG Q,CHEN J,LI X X,et al.Research advances on antibacterial peptides from Hermetia illucens[J].Natural Product Research and Development,2021,33(11):1982-1989.(in Chinese)
[24] LI Z,MAO R,TENG D,et al.Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus[J].Scientific Reports,2017,7(1):12124.
[25] VAN MOLL L,DE SMET J,PAAS A,et al.In vitro evaluation of antimicrobial peptides from the black soldier fly (Hermetia illucens) against a selection of human pathogens.[J].Microbiology Spectrum,2022,10(1):e166421.
[26] JIN X,ZHOU J,RICHEY G,et al.Undecanoic acid,lauric acid,and n-tridecanoic acid inhibit Escherichia coli persistence and biofilm formation[J].Journal of Microbiology and Biotechnology,2021,31(1):130-136.
[27] HERDIYATI Y,ASTRID Y,SHADRINA A A N,et al.Potential fatty acid as antibacterial agent against oral bacteria of Streptococcus mutans and Streptococcus sanguinis from basil (Ocimumamericanum):In vitro and in silico studies[J].Current Drug Discovery Technologies,2021,18(4):532-541.
[28] SURENDRA K C,TOMBERLIN J K,VAN HUIS A,et al.Rethinking organic wastes bioconversion:Evaluating the potential of the black soldier fly (Hermetia illucens (L.)) (Diptera:Stratiomyidae) (BSF)[J]. Waste Management,2020,117:58-80.
[29] SPRANGHERS T,OTTOBONI M,KLOOTWIJK C,et al.Nutritional composition of black soldier fly (Hermetia illucens) prepupae reared on different organic waste substrates[J].Journal of the Science of Food and Agriculture,2017,97(8):2594-2600.
[30] JACKMAN J A,BOYD R D,ELROD C C.Medium-chain fatty acids and monoglycerides as feed additives for pig production:Towards gut health improvement and feed pathogen mitigation[J].Journal of Animal Science and Biotechnology,2020,11:44.
[31] WA AS＇ KO A,BULAK P,POLAK-BERECKA M,et al.The first report of the physicochemical structure of chitin isolated from Hermetia illucens[J].International Journal of Biological Macromolecules,2016,92:316-320.
[32] WETHTHASINGHE P,ROCHA S D C,YS O,et al.Modulation of Atlantic salmon (Salmo salar) gut microbiota composition and predicted metabolic capacity by feeding diets with processed black soldier fly (Hermetia illucens) larvae meals and fractions[J].Animal Microbiome,2022,4(1):9.
[33] NEYRINCK A M,POSSEMIERS S,VERSTRAETE W,et al.Dietary modulation of clostridial cluster XIVa gut bacteria (Roseburia spp.) by chitin-glucan fiber improves host metabolic alterations induced by high-fat diet in mice[J].The Journal of Nutritional Biochemistry,2012,23(1):51-59.
[34] PARISI G P V I.Effect of Tenebrio molitor larvae meal on growth performance,in vivo nutrients digestibility,somatic and marketable indexes of gilthead sea bream (Sparusaurata)[J].Animal Feed Science and Technology,2017,226:12-20.
[35] DA SILVA C A,HARTL D,LIU W,et al.TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation[J].Journal of Immunology,2008,181(6):4279-4286.
[36] MARTIN-GALLAUSIAUX C,MARINELLI L,BLOTTIRE H M,et al.SCFA:Mechanisms and functional importance in the gut[J].The Proceedings of the Nutrition Society,2021,80(1):37-49.
[37] DOSTAL A,LACROIX C,BIRCHER L,et al.Iron modulates butyrate production by a child gut microbiota in vitro[J].mBio,2015,6(6):e1415-e1453.
[38] PESSIONE E.Lactic acid bacteria contribution to gut microbiota complexity:Lights and shadows[J].Frontiers in Cellular and Infection Microbiology,2012,2:86.
[39] JIN X,YUAN B,LIU M,et al.Dietary Hermetia illucens larvae replacement alleviates diarrhea and improves intestinal barrier function in weaned piglets challenged with enterotoxigenic Escherichia coli K88[J].Frontiers in Veterinary Science,2021,8:746224.
[40] 金鑫鑫.黑水虻虫粉对断奶仔猪生长性能及对ETEC所致腹泻的影响[D].长春:吉林大学,2021. JIN X X.Effect of Hermetia illucens larvae on growth performance of weaned piglets and diarrhea caused by ETEC[D].Changchun:Jilin University,2021.(in Chinese)
[41] YU M,LI Z,CHEN W,et al.Hermetia illucens larvae as a potential dietary protein source altered the microbiota and modulated mucosal immune status in the colon of finishing pigs[J].Journal of Animal Science and Biotechnology,2019,10:50.
[42] 余苗,李贞明,王刚,等.黑水虻幼虫粉对育肥猪盲肠食糜主要微生物数量和代谢产物的影响[J].畜牧兽医学报,2020,51(2):299-310. YU M,LI Z M,WANG G,et al.Effects of Hermetia illucens larvae meal on the number of main microbes and metabolites in the cecum of finishing pigs[J].Acta Veterinaria et Zootechnica Sinica,2020,51(2):299-310.(in Chinese)
[43] BIASATO I,RENNA M,GAI F,et al.Partially defatted black soldier fly larva meal inclusion in piglet diets:Effects on the growth performance,nutrient digestibility,blood profile,gut morphology and histological features[J].Journal of Animal Science and Biotechnology,2019,10:12.
[44] BIASATO I,FERROCINO I,COLOMBINO E,et al.Effects of dietary Hermetia illucens meal inclusion on cecal microbiota and small intestinal mucin dynamics and infiltration with immune cells of weaned piglets[J].Journal of Animal Science and Biotechnology,2020,11:64.
[45] TAHAMTANI F M,IVARSSON E,WIKLICKY V,et al.Feeding live black soldier fly larvae (Hermetia illucens) to laying hens:Effects on feed consumption,hen health,hen behavior,and egg quality[J].Poultry Science,2021,100(10):101400.
[46] BELLEZZA O S,BIASATO I,IMARISIO A,et al.Black soldier fly and yellow mealworm live larvae for broiler chickens:Effects on bird performance and health status[J].Journal of Animal Physiology and Animal Nutrition,2021,105 (Suppl 1):10-18.
[47] HARTINGER K,GREINIX J,THALER N,et al.Effect of graded substitution of soybean meal by Hermetia illucens larvae meal on animal performance,apparent ileal digestibility,gut histology and microbial metabolites of broilers[J].Animals:An Open Access Journal from MDPI,2021,11(6):1628.
[48] BOVERA F,LOPONTE R,PERO M E,et al.Laying performance,blood profiles,nutrient digestibility and inner organs traits of hens fed an insect meal from Hermetia illucens larvae[J].Research in Veterinary Science,2018,120:86-93.
[49] HE C,LEI J,YAO Y,et al.Black soldier fly (Hermetia illucens) larvae meal modulates intestinal morphology and microbiota in Xuefeng Black-bone chickens[J].Frontiers in Microbiology,2021,12:706424.
[50] BIASATO I,FERROCINO I,DABBOU S,et al.Black soldier fly and gut health in broiler chickens:Insights into the relationship between cecal microbiota and intestinal mucin composition[J].Journal of Animal Science and Biotechnology,2020,11:11.
[51] CUTRIGNELLI M I,MESSINA M,TULLI F,et al.Evaluation of an insect meal of the black soldier fly (Hermetia illucens) as soybean substitute:Intestinal morphometry,enzymatic and microbial activity in laying hens[J].Research in Veterinary Science,2018,117:209-215.
[52] MONIELLO G,ARIANO A,PANETTIERI V,et al.Intestinal morphometry,enzymatic and microbial activity in laying hens fed different levels of a Hermetia illucens larvae meal and toxic elements content of the insect meal and diets[J].Animals:An Open Access Journal from MDPI,2019,9(3):86.
[53] GARIGLIO M,DABBOU S,BIASATO I,et al.Nutritional effects of the dietary inclusion of partially defatted Hermetia illucens larva meal in muscovy duck[J].Journal of Animal Science and Biotechnology,2019,10:37.
[54] SYPNIEWSKI J,KIERO AN＇G CZYK B,BENZERTIHA A,et al.Replacement of soybean oil by Hermetia illucens fat in turkey nutrition:Effect on performance,digestibility,microbial community,immune and physiological status and final product quality[J].British Poultry Science,2020,61(3):294-302.
[55] SEKIROV I,RUSSELL S L,ANTUNES L C M,et al.Gut microbiota in health and disease[J].Physiological Reviews,2010,90(3):859-904.
[56] ZHANG S,ZHONG G,SHAO D,et al.Dietary supplementation with Bacillus subtilis promotes growth performance of broilers by altering the dominant microbial community[J].Poultry Science,2021,100(3):100935.
[57] BERGER K,BURLEIGH S,LINDAHL M,et al.Xylooligosaccharides increase Bifidobacteria and Lachnospiraceae in mice on a high-fat diet,with a concomitant increase in short-chain fatty acids,especially butyric acid[J].Journal of Agricultural and Food Chemistry,2021,69(12):3617-3625.
[58] PENG L,LI Z,GREEN R S,et al.Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers[J].The Journal of Nutrition,2009,139(9):1619-1625.
[59] BORRELLI L,CORETTI L,DIPINETO L,et al. Insect-based diet,a promising nutritional source,modulates gut microbiota composition and SCFAs production in laying hens[J].Scientific Reports,2017,7(1):16269.
[60] DABBOU S,LAUWAERTS A,FERROCINO I,et al.Modified black soldier fly larva fat in broiler diet:Effects on performance,carcass traits,blood parameters,histomorphological features and gut microbiota[J].Animals:An Open Access Journal from MDPI,2021,11(6):1837.
[61] BORRELLI L,CORETTI L,DIPINETO L,et al.Insect-based diet,a promising nutritional source,modulates gut microbiota composition and SCFAs production in laying hens[J].Scientific Reports,2017,7(1):16269.

Research Advances of Hermetia illucens on Intestinal Health and Microflora in Pigs and Poultry

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	WU Liting, LU Rui, LIU Banhong, BAO Hongduo, WANG Yongjuan, ZHOU Yan, WANG Ran, ZHANG Hui. Combination of Clostridium perfringens Phage and Lactobacillus Improves Growth Performance and Regulates Intestinal Flora Function of Broilers [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2321-2332.
[2]	ZHANG Huaqiang, WANG Pinsheng, LI Xiao, WEI Panpeng, YAN Lingmin, JIANG Bingbing, WANG Zhaogui, WANG Xuefang, ZENG Huanqing, FAN Yi, GAO Zhenglong, WANG Xuebing. Effects of Fermented Hybrid Broussonetia papyrifera on Growth Performance, Meat Quality,Digestive Enzyme Activity and Intestinal Flora Structure of Hu Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1876-1887.
[3]	XIONG Taidi, JIANG Shouqun, ZHANG Huihua, ZHU Cui. Research Progress on Transportation Stress and Its Mitigation Measures in Poultry [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 977-988.
[4]	LIU Bin, LI Meng, XI Qianyun, SUN Jiajie, LUO Junyi, ZHANG Yongliang, CHEN Ting. Research Progress on Biological Characteristics of Hermetia illucens L. and Its Application in Poultry Production [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 586-597.
[5]	SHI Jiancun, LI Jikai, JIA Lin, LYU Jiancun, SHANG Zihan, ZHANG Tie, WANG Chunguang. Effects of Fermented Traditional Chinese Medicine on the Growth Performance, Antibody Level and Intestinal Flora of Laying Hens [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(6): 2145-2155.
[6]	WANG Zhihua, JIA Junpeng, RADEBE Stoffel Matjeke, YU Qinghua. Study on the Growth Performance and Intestinal Flora of Beagle Puppies Regulated by Probiotics [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(2): 510-520.
[7]	ZHAO Dehui, ZHANG Haihua, WANG Jinming, MA Cuiliu, LIU Hanlu. Research Progress on Maintain Intestinal Health and Antiviral Effect of Probiotics [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(11): 4252-4260.
[8]	GENG Shuang, GENG Chunyin, YANG Meng, ZHANG Min. The Influence of Two Different Kinds of Antibiotic-free Addictive on Growth and Intestinal Health of Growing Pigs [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(4): 1240-1250.
[9]	PENG Qiaoli, QI Qien, ZHOU Guoyong, TANG Min, CHEN Dongling, LIU Shen, ZHANG Huihua. Effects of Fermented Shiitake Residues on Growth Performance, Colonic Volatile Fatty Acids Contents and Microbial Structure in Weaned Piglet [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(11): 3985-3995.
[10]	LIANG Xiaorui, WANG Danyang, QIAO Yanjie, ZHANG Baojun, SUN Guojie, SHAO Yongbin, GU Xinli, LUO Yan. Effects of Water Extract of Three Qingre Chinese Medicine on Intestinal Flora and Mucosal Barrier Function of Broilers [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(7): 2043-2054.
[11]	WANG Min, PENG Peiyuan, YANG Tai, DENG Pan, TIAN Kexiong. A Regulation Mechanism of Mannan Oligosaccharide on Intestinal Health and Immunity and Its Application in Livestock and Poultry Production [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(2): 433-441.
[12]	GU Yanli, SHAN Chunqiao, CAO Yanzi, LIU Yan, LIN Yang, WANG Xiaoyu, JIANG Guotuo. Effect of Fermented Traditional Chinese Medicine on Preventing and Treating Colibacillosis and Immune Regulation in Broilers [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(11): 3687-3695.
[13]	TIAN Qizhen, TANG Chenchen, SHEN Danqing, LU Wei, CAI Bingyan. The Effects of Lactobacillus salivarius TCSL1 on Growth Performance,Hematology, Serum Biochemical Indexes and Intestinal Health in Puppies [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(11): 3757-3766.
[14]	ZHOU Yongchun, WANG Kunlun, YAN Yaqun, ZHAO Shanshan, NING Changshen. Advances on the Interaction Between Intestinal Parasites and Flora [J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(10): 2876-2881.
[15]	GU Wei, SUN Mingjie, WANG Lirong, CHEN Zhen, ZENG Jiajia, CHEN Jing, XU Haiyan, WANG Chunfeng. Effects of Four Kinds of Traditional Chinese Medicine on Immune Performance and Intestinal Flora in Immunosuppressed Mice [J]. , 2019, 46(1): 147-156.