China Animal Husbandry and Veterinary Medicine ›› 2022, Vol. 49 ›› Issue (10): 3819-3828.doi: 10.16431/j.cnki.1671-7236.2022.10.014

• Nutrition and Feed • Previous Articles     Next Articles

Effects of Astragalus Polysaccharide Supplementation on Milk Yield,Immune and Antioxidant Performance of Dairy Cows

XU Liyun1, ZHENG Menghe1, XU Zihao1, NIU Gaowei2, WANG Yongli3, QIU Hui4, WU Yuxuan4, JIN Tong4, SHAO Wei1   

  1. 1. College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China;
    2. Xinjiang Evergreen Feed Co., Ltd., Changji 831100, China;
    3. Xinjiang Jiahe Ruixin Agriculture and Animal Husbandry Technology Co., Ltd., Changji 831100, China;
    4. Xinjiang Changji Jiyuan Animal Husbandry Co., Ltd., Changji 831100, China
  • Received:2022-04-24 Online:2022-10-05 Published:2022-09-30

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Abstract: 【Objective】 This experiment was conducted to investigate the effects of Astragalus polysaccharide (APS)on milk yield,immune function and antioxidant performance of dairy cows.【Method】 Forty-four Chinese Holstein dairy cows with good body condition,similar body weight,milk yield,lactation days and parity were randomly divided into control group(CK),APS20,APS55 and APS90 groups,with 11 cows in each group.All experimental cattle were fed with basal diet.The control group was given 200 mL warm water,and the experimental groups were given 200 mL APS solution of 20,55 and 90 g/d,respectively,the pre-test period lasted for 10 days,and the formal test period lasted for 60 days.During the normal feeding period,milk yield was counted every 10 days.Milk samples were collected at 0,30th and 60th days of normal feeding period,and milk somatic cell count(SCC) was determined.The blood samples of tail root vein were collected before morning feeding on day 0,30th and 60th of normal feeding period,and the related immune indexes and antioxidant indexes in serum were determined.【Result】 During the whole experiment period,there was no significant difference in milk yield among all groups (P＞0.05).In terms of somatic cell count,compared with CK group,on the 30th and 60th days, the SCS of APS55 group was significantly decreased (P＜0.05),the SCS of APS20 and APS90 groups had no significant difference at all time points (P＞0.05),and the SCS of APS90 group was significantly higher than APS55 group (P＜0.01).In terms of immune indicators,compared with CK group,on the 30th day,the serum IL-2 content in APS20 group was significantly increased (P＜0.05),and the serum IL-2 contents in APS55 and APS90 groups were extremely significantly increased (P＜0.01).On the 60th day,the serum IL-2 contents in APS20,APS55 and APS90 groups were extremely significantly increased (P＜0.01),and the IL-2 contents in APS55 and APS90 groups were extremely significantly higher than that in APS20 group (P＜0.01).On the 60th day,the serum IL-6 content of APS55 group was significantly increased (P＜0.05).In terms of antioxidant indexes,compared with CK group,serum CAT activity in APS20,APS55 and APS90 groups was extremely significantly increased on the 30th and 60th days (P＜0.01);On the 60th day,the serum MDA concentration in ASP90 group was significantly decreased (P＜0.05),the serum GSH-Px concentration in APS20,APS55 and APS90 groups was significantly increased (P＜0.05),and the serum T-AOC activity in APS55 and APS90 groups was extremely significantly increased (P＜0.01) and was significantly higher than that in APS20 group (P＜0.05).【Conclusion】 APS 55 g/d could improve immune function and antioxidant capacity of dairy cows,and reduce milk somatic cell count,the results provided references for the application of APS in dairy production.

Key words: Astragalus polysaccharide; milk yield; somatic cell score; immune; antioxidant

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