猪重大育种价值基因及挖掘技术研究进展

doi:10.16431/j.cnki.1671-7236.2022.03.021

Abstract

Abstract: With the rapid development of molecular biology and animal genetics and breeding technology, the research on fine traits of livestock and poultry has also moved from phenotypic breeding to molecular breeding of genes associated with single or multiple important traits.For example, the research on the meat quality trait of pigs has obtained many key genes in affecting the backfat thickness, intramuscular fat content, ham weight and so on.In recent years, African swine fever has caused a great blow to the pig industry, and the research on pig disease has once again become a hot spot.In the study of disease resistance traits in pigs, many key genes, such as CD163, are directly involved in the invasion mechanism of Porcine respiratory and reproductive syndrome virus.In addition to the influence of disease, the reproductive traits of pigs also play a vital role in the development of pig industry.With the in-depth study of important traits, a large number of multidimensional data of important breeding value genes have been accumulated, and a variety of gene screening techniques have been developed, especially the discovery of CRISPR-Cas9 gene editing technology and its successful application as a genome-wide screening tool, as well as the combined application of functional genomic screening and multi-omics in the post-genomic era, the application and development of these technologies have further promoted the development of the field of genetic breeding.The author systematically summarized important breeding value genes related to meat, disease resistance and reproductive traits and their mining technology in pigs, in orded to provide guiding suggestions and references for the genetic improvement of pigs.

Key words: pig; meat quality; disease resistance; reproductive; molecular markers

CLC Number:

S813.3

FANG Qianhai, CHEN Hongbo, BI Yanzhen. Research Progress on Important Breeding Value Genes and Screening Techniques of Pigs[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(3): 992-1004.

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Research Progress on Important Breeding Value Genes and Screening Techniques of Pigs

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