丁酸钠对鱼类肠道消化吸收的影响研究进展

doi:10.16431/j.cnki.1671-7236.2022.01.014

Abstract

Abstract: Fish have an imperfect digestive system and low digestive enzyme activity compared with livestock and poultry animals. Plant raw materials often contain anti-nutritional factors and toxic components, resulting in intestinal injury, enteritis, and other diseases. Short-chain fatty acids such as butyric acid can significantly improve fish growth performance, enhance fish health, antioxidant and anti-stress ability. Due to the poor smell of butyric acid affecting the palatability of animals, sodium butyrate, as a substitute for butyric acid, is solid and non-volatile, easy to add and use. Sodium butyrate can promote the development of intestinal epithelial cells, improve the intestinal morphological structure, maintain the integrity of intestinal mucosal barrier, repair the damaged intestinal mucosa, stimulate the synthesis of mRNA and protein in epithelial cells, accelerate the proliferation of intestinal epithelial cells, increase the height of villi, and promote digestion and absorption. Sodium butyrate can destroy the DNA structure of harmful bacteria, and protein can not be synthesized, so that harmful bacteria can not normally divide, inhibit the growth and reproduction of harmful intestinal bacteria, promote the proliferation of beneficial bacteria, maintain the balance of intestinal flora, and significantly improve the diversity of flora. Sodium butyrate can improve fish digestion by stimulating the secretion of digestive enzymes, reduce the intestinal damage caused by poor protein raw materials, inhibit the apoptosis of fish intestinal cells, reduce the occurrence of intestinal inflammation, and significantly improve the function of fish intestinal barrier. Sodium butyrate can be used as a growth promoter and immune stimulant, reduce cost in low fish meal feed and improve fish growth and development. Therefore, sodium butyrate is a green and safe additive that can replace antibiotics, and plant protein can appropriately replace fish meals to improve economic benefits. The author focuses on the effect of sodium butyrate on intestinal digestion and absorption to provide a scientific reference for the application of sodium butyrate in fish and other aquaculture.

Key words: sodium butyrate; fish; intestine; digestion and absorption

CLC Number:

S816.71

LI Xiang, HE Jinhuan, PAN Chunmei, SUO Jianghua, LI Jing. Research Progress on Effects of Sodium Butyrate on Intestinal Digestion and Absorption of Fish[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(1): 131-139.

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Research Progress on Effects of Sodium Butyrate on Intestinal Digestion and Absorption of Fish

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