›› 2018, Vol. 45 ›› Issue (7): 1841-1848.doi: 10.16431/j.cnki.1671-7236.2018.07.014

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Effects of Adding Different Levels of Sodium Butyrate on Growth Performance, Diarrhea Rate and Blood Biochemical Indexes of Weaned Piglets

KOU Shasha, WANG Zhaosheng, XU Dewang, LIANG Jing, ZHANG Wenju, NIE Cunxi   

  1. College of Animal Science and Technology, Shihezi University, Shihezi 832000, China
  • Received:2018-02-09 Online:2018-07-20 Published:2018-07-20

Abstract:

The experiment was aimed to study the effects of adding different levels of sodium butyrate on the growth performance,diarrhea rate and blood biochemical indexes of weaned piglets.240 healthy weaned piglets (Duroc×Landrace×Yorkshire) at age of (21±2) days were selected and randomly divided into five groups according to the principles of nest and body weight,namely,groups Ⅰ to Ⅴ,with 3 replicates per group and 16 piglets per replicate.Group Ⅰ was the control group,the diet of group Ⅱ was supplemented with 0.01% antibiotics while that of groups Ⅱ,Ⅳ and Ⅴ were added 0.1%, 0.2% and 0.3% sodium butyrate, respectively.The experiment lasted for 28 days.The body weight of weaned piglets were measured at 0,7,14,24 and 28 d,and ADG,ADFI, F/G,diarrhea rate and diarrhea indexes were measured during the experiment.The blood samples were collected from 6 piglets per group to determine the blood biochemical indexes.The results showed that compared with group Ⅰ,the addition of sodium butyrate in weaned piglets diets significantly increased the ADG in groups Ⅳ and Ⅴ at first,second,third weeks and the whole period (P<0.05).Supplementation of sodium butyrate significantly increased the ADFI in groups Ⅲ,Ⅳ and Ⅴ at the second,third weeks and whole period (P<0.05).The F/G of groups Ⅱ,Ⅲ,Ⅳ and Ⅴ were decreased at second,third,four weeks and the whole period (P>0.05),while that in groups Ⅳ and Ⅴ were decreased significantly at first week (P<0.05).The diarrhea rate and diarrhea index in groups Ⅱ,Ⅲ and Ⅳ did not change significantly (P>0.05).The diarrhea rate (P<0.05) and the diarrhea index (P>0.05) in group Ⅴ was increased.Compared with group Ⅰ,the levels of serum phosphorus in groups Ⅲ,Ⅳ and Ⅴ were significantly increased (P<0.05), and the levels of serum calcium and total protein in group Ⅴ were significantly increased (P<0.05),while the triglyceride content of groups Ⅳ and Ⅴ were significantly increased than that of groups Ⅰ,Ⅱ and Ⅲ (P<0.05).There was no significant change in serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, urea nitrogen and albumin among all groups (P>0.05).In conclusion, adding sodium butyrate to the diet of weaned piglets had the effect of promoting growth performance and improving health,and the optimum amount of sodium butyrate was 0.2%.

Key words: sodium butyrate; weaned piglets; growth performance; biochemical indexes

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