组学技术在乳酸菌分离鉴定及功能研究中的应用

doi:10.16431/j.cnki.1671-7236.2020.12.010

Abstract

Abstract: Lactic acid bacteria can promote host health by adhering to host cells or mucosa and inhibiting pathogen growth,maintaining microecological balance and enhancing host immunities.It also plays an important role in food industry,antimicrobial production and in vivo fermentation.However,the specific molecular mechanism of probiotics in lactic acid bacteria is rarely described.In order to explore the new function and regulation mechanism of lactic acid bacteria itself and lactic acid bacteria in its host,omics technology can be used for research.The omics methods derived from the central dogma include genomics,transcriptomics,proteomics,and metabolomics.The application of monoomics technology in the study can further explore the function and mechanism of lactic acid bacteria.The application of multi-group technology can break through the limitation of single group technology,the potential function of lactic acid bacteria can be analyzed synthetically from different dimensions,and the lactic acid bacteria itself and its role in the host were further predicted.Several omics techniques which are commonly used in the field of lactic acid bacteria isolation and identification and functional research were reviewed in this paper.The application of multi-omics in the study of function and mechanism of lactic acid bacteria were reviewed.It provided a feasible technical method and direction to further explore the potential function of lactic acid bacteria.

Key words: lactic acid bacteria; genomic; transcriptomics; proteomics; metabolomics; multi-omics

CLC Number:

S852.1

NIU Chunyu, SHI Linlin, SUN Miao, LIU Yanmin, HUANG Shaolei, CHENG Chao, LI Peifeng. Applications of Omics Approaches in Isolation and Identification of Lactic Acid Bacteria and It’s Functional Research[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(12): 3882-3889.

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Applications of Omics Approaches in Isolation and Identification of Lactic Acid Bacteria and It’s Functional Research

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