China Animal Husbandry and Veterinary Medicine ›› 2020, Vol. 47 ›› Issue (10): 3203-3213.doi: 10.16431/j.cnki.1671-7236.2020.10.019

• Animal Nutrition and Feed Science • Previous Articles     Next Articles

Antibacterial Mechanism of Pediococcus and Its Application in Livestock and Poultry Production

TAN Keqin1, TANG Jiahong2, MA Xianyong1, DENG Dun1   

  1. 1. Guangdong Provincial Poultry Meat Quality, Quality Control and Evaluation Engineering Technology Center, Guangdong Provincial Animal Breeding and Nutrition Public Laboratory, South China Key Laboratory of Animal Nutrition and Feed, Ministry of Agriculture and Rural Affairs, State Key Laboratory of Animal Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
    2. Department of Bioengineering, Jinan University, Guangzhou 510632, China
  • Received:2020-01-16 Online:2020-10-20 Published:2020-10-17

Abstract: Finding antibiotic alternatives is a major issue in the breeding industry.Pediococcus, a kind of Gram-positive lactic acid bacteria,is one of the probiotics allowed in the feed addition catalogue.A large number of studies have shown that Pediococcus has great application value in the food,medical and breeding industries.Their good colonization ability on the surface of the host intestinal mucosal cells reduces the adhesion of other bacteria.Meanwhile,Pediococcus is able to produce many antibacterial substances including pediocin,organic acids and hydrogen peroxide.Therefore,it's showing their good probiotic performance in inhibiting the growth of pathogenic bacteria,improving the intestinal microbial community structure,stimulating the host's immunity,promoting the health of farmed animals,and improving animal growth performance,However,compared with other probiotics,its degree of attention is not high.This article summarizes the types of bacteriostatic substances produced by Pediococcus and their bacteriostatic mechanisms,introduces Pediococcus's adhesion and immune regulation,and the application of Pediococcus in the production of animals such as pigs and chickens.The aim was to provide a theoretical reference for Pediococcus's reasonable application in animal production.The results discussed in this article indicated that Pediococcus had broad-spectrum,stable bacteriostatic effects and rich probiotic properties.It's beneficial to the healthy growth of livestock and poultry,prevents pathogenic bacterial infections,and reduces the incidence of diseases.Therefore,Pediococcus is worth increasing its promotion and application.

Key words: Pediococcus; pediocins; antibacterial mechanisms; probiotics; livestock breeding

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