›› 2015, Vol. 42 ›› Issue (8): 2124-2130.doi: 10.16431/j.cnki.1671-7236.2015.08.029

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Genetic Polymorphism of Dppa5 Gene and its Association with Reproductive Performance in Sow

LU Hui-wen1,2, GUO Ruo-ting1, LIU Hong-jie2, HUANG Tao1   

  1. 1. College of Animal Science and Technology, Shihezi University, Shihezi 832003, China;
    2. TECON Animal Husbandry Technology Corporation, Changji 831100, China
  • Received:2014-12-10 Online:2015-08-20 Published:2015-08-27

Abstract: The purpose of this study was to detect the genetic variation of the porcine developmental piuripotency associated 5 (Dppa5) gene and its association with reproductive performance in sow.PCR-RFLP and sequencing methods were used to detect SNPs and analyze its association with reproductive performance in Large White and Landrace sows.The results showed that two missense mutations g.363 T> C and g.844 G> T were detectd in exon of porcine Dppa5.SNP g.363 T> C affected total number born highly significantly in primiparous Large White sow (P< 0.01) and affected litter size and number born alive significantly in Large White and Landrace sows (P< 0.05).SNP g.844 G> T showed a significant impact on total number born in multiparous Landrace and Large White sows (P< 0.05).The results suggested that the SNPs of Dppa5 gene impacted reproductive performance of sows and could be genetic markers.

Key words: pig; Dppa5 gene; reproductive performance

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