›› 2015, Vol. 42 ›› Issue (5): 1311-1317.doi: 10.16431/j.cnki.1671-7236.2015.05.042

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Research Progress on Porcine Reproductive and Respiratory Syndrome Virus Vertical Transmission and its Hazards

LI Tao-mei1,2, LAI Zhi3, CUI Li1   

  1. 1. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China;
    2. Shanghai ECO-BIOK Veterinary Drugs Distribution Co., Ltd., Shanghai 200042, China;
    3. Shanghai Chuanghong Bio-Tech Co., Ltd., Shanghai 201419, China
  • Revised:2014-11-11 Online:2015-05-20 Published:2015-06-02

Abstract: Productive disorder induced by porcine reproductive and respiratory syndrome virus (PRRSV) is characterized by low conception rate, irregular return to estrus and abortion during early gestation sow; Later-term abortion, early farrowing, stillborn, mummies and weak-born piglets are generally happened at second half of gestation.Piglets with congenital infection become more sensitive to secondary infection, and there exists excreted virus which infects the negative animals on every side.PRRSV passes through the placenta mediated by macrophages/monocytes, which cause pathological damage in the maternal-fetal interface, and virus replication in the fetal implantation sites plays a role in the fetal death and sow abortion.PRRSV infection prevention and viremia shortening for sow are conductive to reduce PRRSV vertical transmission.In addition, biosafety measures, reasonable pig flow and strict disinfection are carried out to control horizontal transmission, and vaccine immunization and medicine administration are done to protect susceptible animals.The main purpose of this review is to summarize PRRSV vertical transmission during each stage of gestation and subsequent reproductive failure.

Key words: porcine reproductive and respiratory syndrome virus; vertical transmission; congenital infection; viremia

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