Abstract: In order to construct the assessment model of general disease resistance in Yorkshire, eight important cytokines levels (IL-1β, IL-4, IL-6, IL-8, IL-10, TGF-β, TNF-α and IFN-γ) were detected in 30-day-age Yorkshire piglets, respectively, and then the principal component analysis was carried out on the immune traits. The results showed that fore 5 character values were selected as the principal components (occupied 87.721% of accumulative contribution rate), and these five components contained nearly all the original information. The combined scores of diarrheal and health weaning piglets in 30-day-age were compared by the assessment model in different genotype population, and the results showed that the combined score of weaning piglets of health group was 0.080, and weaning piglets of diarrheal group was -0.009.This study initially identified the main components which affected the general disease resistance of Yorkshire, and made the preliminary verification of it. The result provided some guidance and theoretical basis for the early disease resistance breeding of Yorkshire in the future.

Key words: pig; general disease resistance; principal component analysis