加味四君子汤对脾虚小鼠免疫机能、抗应激和消化吸收的影响

doi:10.11843/j.issn.1671-7236.2015.03.032

Abstract

Abstract: This experiment was conducted to study pharmacodynamics of supplemantary sijunzi decoction (SJZD).In order to evaluate the effect of SJZD on the general signs,immune function,anti-stress,gastrointestinal motility and absorption of spleen deficiency mice,the model of spleen deficiency was prepared with rheum officinale solution.The results showed that the general signs were improved,body weight,body temperature of spleen deficiency mice and devouring percentage of macrophage cell were significantly increased in high dosage-treated groups (P <0.05).The content of serum IgM,spleen and thyrus index were singficantly increased in medium dosage-treated group (P <0.05).The devouring index of macrophage cell and swimming duration were significantly increased in various dosage of supplemantary SJZD (P <0.05),anti-hypoxia ability could be prolonged,gastric emptying rate and relative percentage each small intestine propulsion were decreased in various dosage of SJZD,D-xylose excretion contents and serum amylase activities were enhanced in various dosage of supplemantary SJZD.In conclusion,SJZD could improve the spleen deficiency symptoms,enhance the immune function,anti-stress ability and gastrointestinal motility.

Key words: supplemantary sijunzi decoction; rheum officinale solution; spleen deficiency models; mice

CLC Number:

S853.7

LI Yu, SUN Zhi-kuo, WANG Xi-chun, TANG Ji-shun, FENG Shi-bin, MENG Qing-juan, WU Jin-jie. Effect of Supplemantary Sijunzi Decoction on Immune Function,Anti-stress, Digestion and Absorption of Spleen Deficiency Mice[J]. , 2015, 42(3): 714-720.

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Effect of Supplemantary Sijunzi Decoction on Immune Function,Anti-stress, Digestion and Absorption of Spleen Deficiency Mice

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