›› 2014, Vol. 41 ›› Issue (11): 278-282.

• 疾病防治 • 上一篇    下一篇

硫酸头孢喹肟乳房注入剂对泌乳期奶牛的安全性研究

闫星1, 刘义明1, 路永强2, 张道康1, 刘茂林1, 张宁3, 王天坤4, 郭江鹏2, 李秀波1   

  1. 1. 中国农业科学院饲料研究所, 北京 100081;
    2. 北京市畜牧兽医总站, 北京 100012;
    3. 中国农业大学, 北京 100193;
    4. 昌平区动物疫病预防控制中心, 北京 102200
  • 收稿日期:2014-05-16 出版日期:2014-11-20 发布日期:2014-12-06
  • 通讯作者: 李秀波 E-mail:lixiubo@mail.caas.cn
  • 作者简介:闫星(1989-),女,河南人,硕士生,研究方向:新兽药研发及药物分析。

Safety Study on Cefquinome Sulfate Intramammary Infusion of Lactating Cows

YAN Xing1, LIU Yi-ming1, LU Yong-qiang2, ZHANG Dao-kang1, LIU Mao-lin1, ZHANG Ning3, WANG Tian-kun4, GUO Jiang-peng2, LI Xiu-bo1   

  1. 1. Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
    2. Beijing Animal Husbandry and Veterinary Station, Beijing 100012, China;
    3. China Agricultural University, Beijing 100193, China;
    4. Changping District Animal Disease Prevention and Control Center, Beijing 102200, China
  • Received:2014-05-16 Online:2014-11-20 Published:2014-12-06

摘要: 为研究硫酸头孢喹肟乳房注入剂对泌乳期奶牛的安全性,试验选用12头健康泌乳奶牛(6头初产、6头经产),间隔12 h对每头奶牛的4个乳区分别注入硫酸头孢喹肟乳房注入剂(规格:8 g:75 mg/支)1支,连续给药3次,比较观察给药前后奶牛的临床症状、体细胞数、日产奶量及乳区病原菌变化情况。结果显示,与给药前相比,给药期间及停药后奶牛的临床症状、体细胞数、日产奶量、乳区病原菌检测结果均无显著性差异(P>0.05)。表明硫酸头孢喹肟乳房注入剂对泌乳期奶牛是安全的。

关键词: 硫酸头孢喹肟; 泌乳期; 奶牛; 安全性

Abstract: The aim of the experiment was to research the safety of cefquinome sulfate intramammary infusion for lactating cows.12 healthy lactating cows (6 were primiparous and 6 were multiparous) were selected to inject 1 peice of cefquinome sulfate intramammary infusion (dose:8 g:75 mg/piece) into four dairy regions of each cow for 3 times,and its interval of the administration was 12 h,and the evaluation indicators included the differences of clinical manifestation grade,daily yielding,somatic cells number and the changes of pathogen in dairy regions in milk before and after administration.The results showed that there were no significant differences in indicators all above before or after the treatment (P>0.05),which suggested that cefquinome sulfate intramammary infusion was safe to lactating cows when administrated according to the dosing regimen above.

Key words: cefquinome sulfate; lactation; cows; safety

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