›› 2009, Vol. 36 ›› Issue (8): 131-132.

• 疾病防治 • 上一篇    下一篇

不同类型鸡新城疫La Sota疫苗的免疫应答比较

莫娟1,韩玉林2,陈玉霞1,赵金凤1,郭鑫3,李新生1   

  1. (1.河南农业大学牧医工程学院, 郑州 450002; 2.焦作市畜牧局, 焦作 454000;3.大庆职业学院化学工程系, 大庆 163255)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-08-20 发布日期:2009-08-20
  • 通讯作者: 李新生

Comparing the Immune Response of Different Tyre of Lasota Vaccines against Newcastle Disease Virus

MO Juan1, HAN Yu-lin2, CHEN Yu-xia1, ZHAO Jin-feng1, GUO Xin3, LI Xin-sheng1   

  1. (1.College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; 2. Animal Husbandry Bureau of Jiaozuo City, Jiaozuo 454000, China; 3.Department of Chemical Engineering, Daqing Vocational College, Daqing 163255, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-08-20 Published:2009-08-20
  • Contact: LI Xin-sheng

摘要: A、B、C、D组SPF鸡分别接种La Sota加佐剂活疫苗,未加佐剂活疫苗,氢氧化铝胶佐剂苗和油佐剂灭活疫苗,通过采集血清进行红细胞凝集抑制试验,测定其抗体水平,并进行比较。结果表明,La Sota加佐剂活疫苗组可产生较高的抗体滴度,并持续较长时间;而未加佐剂疫苗组血清阳转较弱,且持续时间较短;油佐剂灭活疫苗组抗体滴度最高,维持时间最长。

关键词: 新城疫; 疫苗; 佐剂; 免疫应答

Abstract: Five groups of SPF chicks were equally divided into A, B, C, D and E. Group A was given adjuvanted La Sota live vaccine. B was given La Sota live vaccine without adjuvant; C and D were given La Sota inactived vaccine with Aluminium Hydroxide Gel Adsorbed and emulsion respectively. Group E was unvaccinated as control.Then five groups were subjected to hemagglutination inhibition (HI) test for assessment of antibody level against NDV. It was showed that group A was detected a comparatively higher level of antibody for a longer period. However, the sero-conversion of group B was comparatively poor. The peak of antibody against NDV La Sota strain in group D was highest and maintained more time than the others groups.

Key words: Newcastle disease; vaccine; adjuvant; immune response