转基因水稻饲用安全性评价的研究进展

摘要/Abstract

摘要： 现代生物技术的发展为利用外源动物、植物、微生物基因培育优良转基因水稻品种提供了新的途径。随着人们对食品安全问题的格外关注,转基因水稻的食用安全性日益成为关注的焦点。作者简要综述了近年来国内外转基因水稻研究现状与安全性评价的最新进展。

关键词: 转基因; 水稻; 饲用安全

Abstract: The development of modern biotechnology provided a new way for the use of exogenous animals,plants,microorganisms genetically bred the excellent genetically modified (GM) rice varieties.Along with people's special concern to food safety,the food security of GM rice was increasingly becoming the focus of attention.A brief overview of the latest progress in the research status and feed security evaluation of GM rice domestic and abroad had been reviewed in this paper.

Key words: genetically modified; rice; feeding safety

中图分类号:

S816.7

曹正辉, 王占彬, 顾宪红. 转基因水稻饲用安全性评价的研究进展[J]. , 2013, 40(11): 88-92.

CAO Zheng-hui, WANG Zhan-bin, GU Xian-hong. Research Progress on the Feed Security Evaluation of Genetically Modified Rice[J]. , 2013, 40(11): 88-92.

参考文献

1 王茵,来伟旗.抗除草剂基因(BAR)转基因水稻的毒性试验[J].卫生研究,2000,29(3):141~142.
2 王瑞懂.武汉消费者对转基因食品的认知研究[D].武汉:华中农业大学,2010.
3 刘宁,沈明浩.食品毒理学[M].北京:中国轻工业出版社,2007.
4 孙锴.转基因水稻对肉仔鸡饲用安全性研究[D]. 南京:南京农业大学,2011.
5 朱德峰,程式华,张玉屏,等.全球水稻生产现状与制约因素分析[J].中国农业科学,2010,43(3):474~479.
6 吴振,顾宪红.转基因食品及食用安全性评价[J].家畜生态学报,2011(2):1~4.
7 张华,王静.转基因食品及其安全性评价[J].粮油与油脂,2004(6):29~31.
8 李丽立,张彬,杨坤明,等.水稻替代玉米饲喂肉鸭对资源和环境的影响[J].长江流域资源与环境,2002(1):60~63.
9 李俊生,肖能文,赵彩云,等.转基因稻米饲料对昆明雄性小白鼠营养效应的影响[J].湖北农业科学,2011,50(19):4013~4017.
10 李科,王世全,吴发强,等.农杆菌介导的转高赖氨酸蛋白基因(sb401)水稻T4代分析[J].中国水稻科学,2008,22:131~136.
11 杜红方.转基因水稻作为肉仔鸡日粮原料的安全性评价[D].北京:中国农业科学院,2006.
12 杨月欣,陈淑蓉,韩军花,等.转SCK基因大米的营养学评价——小型猪比较喂养研究[J].营养学报,2005(1):55~58.
13 苏少泉.转基因作物及其食品安全性[J].中国食物与营养,2004(5):12~14.
14 陈颖,徐宝梁,苏宁,等.实时荧光定量PCR技术检测转基因大豆方法的建立[J].食品与发酵工业,2003,29(8):65~69.
15 陈小萍,卓勤,顾履珍,等.转基因大米营养评价试验[J].营养学报,2004,26(2):119~123.
16 周丽慧,刘巧泉,张昌泉,等.水稻种子蛋白质含量及组分在品种间的变异与分布[J].作物学报,2009,35:884~891.
17 周萍萍,吴永宁,张建.转基因食品检测方法的现况与进展[J] .中国食品卫生杂志,2004,16(3):254~257.
18 周联高.高赖氨酸转基因稻谷对肉仔鸡饲用安全性的研究[D].扬州:扬州大学,2009.
19 胡利华,吴慧敏,周泽民,等.利用农杆菌介导法将柠檬酸合成酶基因(CS)导入籼稻品种明恢86[J].分子植物育种,2006(4):160~166.
20 贺晓云,黄昆仑,秦伟,等.转基因水稻食用安全性评价国内外概况[J].食品科学,2008(12):760~765.
21 郭江,吕林,刘松柏,等.转植酸酶基因玉米对肉仔鸡生长性能、胴体性能及肉品质的影响[J].中国畜牧兽医,2013,40(1):85~88.
22 曹际娟,陈明生,卢行安,等.PCR检测转基因玉米及其粗加工食品[J].玉米科学,2001,9(2):87~91.
23 梁丽."转基因水稻"事件网络传播中的意见领袖研究[D].武汉:华中农业大学,2010.
24 梁雪莲.作物抗除草剂转基因研究进展[J].生物技术通报,2001(7):17~21.
25 舒庆尧,叶恭银,崔海瑞,等.转基因水稻"克螟稻"选育[J].浙江农业大学学报,1998,24:579~580.
26 樊龙江,周雪平,胡秉民,等.转基因的基因漂流风险[J].应用生态学报,2001,12(4):630~632.
27 魏伟,钱迎倩,马克平,等.转基因食品安全性评价的研究进展[J].自然资源学报,2001,16(2):184~190.
28 Cao S,He X,Xu W,et al. Safety assessment of Cry1C protein from genetically modified rice according to the national standards of PR China for a new food resource.Regulatory Toxicology and Pharmacology,2010,58(3):474~481.
29 Castillo A R,Gallardo M R,Maciel M,et al. Effects of feeding rations with genetically modified whole cottonseed to lactating Holstein cows.Journal of Dairy Science,2004,87(6):1778~1785.
30 Christou P,Ford T L,Kofron M. Production of transgenic rice (Oryza sativa L.) plants from agronomically important indica and japonica varieties via electric discharge particle acceleration of exogenous DNA into immature zygotic embryos. Nature Biotechnology,1991(9):957~962.
31 Cromwell G L,Henry B J,Scout A L,et al. Glufosinate herbicide-tolerant (Liberty Link) rice vs. conventional rice in diets for growing-finishing swine. Journal of Animal Science,2005,83:1068~1074.
32 Domon E,Takagi H,Hirose S,et al. 26-week oral safety study in macaques for transgenic rice containing major human T-cell epitope peptides from Japanese cedar pollen allergens. J Agric Food Chem,2009,57: 5633~5638.
33 Fuchs R L,Ream J E,Hammond B G. Safety assessment of he neomycin phosphot ransferase Ⅱ (NPTⅡ) protein. Biol Technol,1993,11:1543~1547.
34 Fujimoto H,Itoh K,Yamamoto M, et al. Insect resistant rice generated by introduction of a modified endotoxin gene of Bacillus thuringiensis.Nature Biotechnology,1993(11):1151~1155.
35 Han J H,Yang Y X,Chen S R,et al. Compairison of nutrient composition of parental rice and rice genetically modified with cowpea trypsin inhibitor in China. Journal of Food Composition and Analysis,2005,18: 297~302.
36 Julie A,Nordlee M S,Taylor S L,et al. Identification of a Brazil-nut allergen in transgenic soybeans. N Engl J Med,1996,334:688~692.
37 Kan C A, Hartnell G F. Evaluation of broiler performance when fed Roundup Ready wheat (event MON 71800),cortrol,and commercial wheat varieties. Poultry Science,2004,3: 1325~1334.
38 Kim T E,Park S W,Cho N Y,et al. Quantitative measurement of serum allergen-specific IgE on protein chip. Experimental and Moleecular Medicine,2002,34: 152~158.
39 Metcalfe D D,Astwood J D,Towsend R,et al. Assessment of the allergenic potential of foods derived from genetically engineered crop plants. Critical Reviews in Food Science and Nutrition,1996,36(Suppl.1):S165~S186.
40 Phipps R H,Deaville E R,Maddison B C.Detection of transgenic and endogenous plant DNA in rumen fluid,duodenal digesta,milk,blood,and feces of lactating dairy cows. J Dairy Sci,2003,86: 4070~4078.
41 Poulsen M,Kroghsbo S,Schroder M,et al. A 90-day safety study in Wistar rats fed genetically modified rice expressing snowdrop lectin Galanthus nivalis(GNA).Food and Chemical Toxicology,2007,45(3): 350~363.
42 Quan R,Hu S,Zhang Z,et al. Overexpression of an ERF transcription factor TSRFI improves rice drought tolerance.Plant Biotechnology Journal,2010,8(4): 476~488.
43 Schroder M,Poulsen M,Wilcks A,et al.90-day safety study of gencitically modified rice expressing Cry1Ab protein (Bacillus thuringiensis toxin) in Wistar rats. Food and Chenmical Toxicology,2007,45(3): 339~349.
44 Séralini G E, Clair E, Mesnate R, et al. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology,2012,50(11):4221~4231.
45 Sharma R,Damgaard D,Alexander T W, et al. Detection of transgenic and endogenous plant DNA in digesta and tissues of sheep and pigs fed Roundup Ready canola meal. Journal of Agriculture Food Chemistry,2006,54(5): 1699~1709.
46 Snell C,Berheim A,Bergé J B,et al. Assessment of the health impact of GM plant diets in long term and multigenerational animal feeding trials: A literature review. Food and Chemical Toxicology,2012,50:1134~1148.
47 Wang Z Y,Wu Z L,Xing Y Y,et al. Nucleotide sequence of rice waxy gene. Nucleic Acids Research,1990,19(18): 5898.

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