枣多糖对免疫抑制蛋雏鸡生长性能和免疫指标的影响

doi:10.16431/j.cnki.1671-7236.2021.09.017

摘要/Abstract

摘要： 为探究金丝小枣多糖（ZJP）对免疫抑制蛋雏鸡生长性能和免疫指标的影响，本试验将900只健康且体重相近的1日龄京红1号蛋鸡随机分为6组，每组6个重复，每个重复25只鸡。Ⅰ组为空白对照组，饲喂基础饲粮；Ⅱ~Ⅵ组在7~9日龄时注射100 mg/kg体重的环磷酰胺，每天1次，建立免疫抑制模型，并分别在基础饲粮中加入600 mg/kg黄芪多糖（APS）及0、400、800和1 600 mg/kg ZJP。试验期为6周。结果显示，ZJP可在不同程度上显著缓解环磷酰胺导致的42日龄体重、22~42和1~42日龄的平均日增重、胸腺和法氏囊指数、聚合免疫球蛋白受体、分泌型免疫球蛋白A （sIgA）及血清中免疫球蛋白A （IgA）和IgG的降低及22~42日龄料重比（F/G）的升高，并且料重比、IgA和IgG达到了APS组的水平。由此得出，在本试验条件下，在基础饲粮中添加适宜水平的ZJP可不同程度改善环磷酰胺所致的生长缓慢和免疫功能低下。

关键词: 金丝小枣多糖; 蛋雏鸡; 免疫抑制; 生长性能; 免疫指标

Abstract: In order to study the effect of Ziziphus jujuba polysaccharide (ZJP) on the growth performance and immune indexes of immunosuppressive egg-type chicks, nine hundred one-day-old Jinghong No. 1 egg-type chicks of healthy and similar body weight were randomly divided into 6 groups with 6 replicates in each group and 25 chickens in each replicate. Group Ⅰ was blank control group, fed with basal diets. The immunosuppressive model was established by injecting 100 mg/(kg·BW) cyclophosphamide once a day at 7-9 days old in groups Ⅱ-Ⅵ, the basic diets were supplemented with 600 mg/kg Astragalus polysaccharides (APS) and 0, 400, 800 and 1 600 mg/kg ZJP, respectively. The trial period was 6 weeks. The results showed that ZJP could significantly alleviate the decrease of body weight at 42 days old, average daily gain at 22-42 days old and 1-42 days old, thymus and bursa index, polymeric immunoglobulin receptor, secretory immunoglobulin A (sIgA) and serum immunoglobulin A (IgA) and IgG, and the increase of F/G at 22-42 days, and the F/G and IgA and IgG reached the level of APS group. Under the conditions of this experiment, adding appropriate level of ZJP to the basal diet could improve the growth retardation and immune dysfunction caused by cyclophosphamide in varying degrees.

Key words: Ziziphus jujuba polysaccharide; egg-type chicks; immunosuppression; growth performance; immune indexes

中图分类号:

S831.5

郭林霞, 马可为, 冯志华, 刘彦慈, 刘观忠, 李清艳, 弓素梅, 李树鹏, 赵国先. 枣多糖对免疫抑制蛋雏鸡生长性能和免疫指标的影响[J]. 中国畜牧兽医, 2021, 48(9): 3264-3272.

GUO Linxia, MA Kewei, FENG Zhihua, LIU Yanci, LIU Guanzhong, LI Qingyan, GONG Sumei, LI Shupeng, ZHAO Guoxian. Effects of Jujube Polysaccharide on Growth Performance and Immune Indexes of Immunosuppressive Egg-type Chicks[J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(9): 3264-3272.

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