食药用真菌多糖的药理作用及其在兽医临床中的应用研究进展

doi:10.16431/j.cnki.1671-7236.2019.10.033

摘要/Abstract

摘要： 食药用真菌不仅给人们提供了大量的健康食品，其次级代谢产物所具有的生物学活性也存在着巨大应用潜力，近年来逐渐受到关注。多糖是食药用真菌的主要活性成分，具有增强机体免疫力、抗病毒、抗氧化、降血脂、降血糖、抗肿瘤、抗辐射、抗溃疡等生物学活性，被称为生物反应调节剂。目前，关于食药用真菌多糖的药理作用研究较为全面，但主要以单一多糖的药理作用研究为主，缺乏多糖之间的协同作用研究。食药用真菌多糖在兽医临床中主要作为调节动物机体免疫力、促生长的饲料添加剂使用，对于其在抗腹泻、抗菌、抗病毒等方面的应用及药理作用机制研究较少。作者主要对食药用真菌多糖的药理作用、构效关系和兽医临床应用等方面的研究进行了综述，并对目前食药用真菌多糖研究中存在的问题进行了分析，对其在兽医临床中的应用前景也做了展望。

关键词: 食药用真菌多糖; 药理作用; 兽医临床; 应用

Abstract: Edible and medicinal fungi not only provide a large number of healthy food for people,but also have great potential applications in the biological activities of secondary metabolites.In recent years,it has attracted more and more attention.Polysaccharides are the main active ingredients of edible and medicinal fungi,which have multiple biological activities such as enhancing the body's immunity,anti-virus,anti-oxidation,lipid-lowering,blood glucose-lowering,anti-tumor,anti-radiation and anti-ulcer.They are internationally known as biological response modifier.At present,the studies on the pharmacological effects of polysaccharides in edible and medicinal fungi are relatively comprehensive and mainly focus on the pharmacological effects of single polysaccharides.Edible-medicinal fungal polysaccharide is mainly used as a feed additive to regulate animal immunity and promote growth in veterinary clinic,but there are few studies on its application in anti-diarrhea,anti-bacterial and anti-virus and its pharmacological mechanism.In this paper,the pharmacological action,structure-activity relationship and veterinary clinical application of edible-medicinal fungal polysaccharides were reviewed,and the existing problems in the study were analyzed and the prospect of its application in veterinary clinic was forecasted.

Key words: edible-medicinal fungal polysaccharide; pharmacologic action; veterinary clinical; application

中图分类号:

Q539

王悦尚, 郑新新, 李富宽, 杨燕, 王慧, 吕慎金. 食药用真菌多糖的药理作用及其在兽医临床中的应用研究进展[J]. 中国畜牧兽医, 2019, 46(10): 3106-3114.

WANG Yueshang, ZHENG Xinxin, LI Fukuan, YANG Yan, WANG Hui, LYU Shenjin. Advances in Pharmacological Action of Polysaccharides from Edible-medicinal Fungi and Its Application in Veterinary Clinic[J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(10): 3106-3114.

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