卵黄抗体在疾病防制中的应用研究进展

doi:10.16431/j.cnki.1671-7236.2017.09.032

摘要/Abstract

摘要：

卵黄抗体（immunoglobulin of yolk，IgY）是指从免疫禽蛋中提取出的针对特定抗原的抗体，是存在于卵黄中的最主要免疫球蛋白，具有化学性质稳定、产量高、成本低、特异性强且无任何毒副作用等特点；且由于动物种系发生距离远，不会发生交叉血清学反应。IgY在动物及人的疾病防制中具有显著优势。作者对IgY的结构特点、理化性质、作用机理及其在各类动物疾病防制方面的应用及发展前景进行了综述，尤其是在动物疾病的治疗方面，如治疗畜禽腹泻及烈性、急性、危害性大的病毒疫病；治疗人类疾病特别是严重危害人类财产安全的人畜共患病；其他方面如水产、皮毛动物等重大疾病。IgY在有效治疗动物疫病的同时，也减少了人畜共患病的可能，从人身安全方面考虑，也必将具有重大发展前景。

关键词: 卵黄抗体; 应用; 畜禽疾病; 人类疾病; 人畜共患病; 前景

Abstract:

Immunoglobulin of yolk (IgY) refers to the specific antibodies from the immune eggs, is the most important immunoglobulin in the yolk,which has the characteristics of stable chemical properties, high yield, low cost, high specificity and no toxic side effects, there was no cross serological reaction among animals breeds because of a long distance. IgY has a significant advantage in animal and human disease prevention and treatment. In this research,we reviewed the application of structural characteristics, physicochemical property and action mechanism of IgY in prevention treatment of animal disease and developing prospect, especially in the treatment of animal diseases, such as diarrhea and acute treatment of animal spirit, harm, large virus disease; zoonosis seriously endanger the safety of human property; Other aspects such as aquaculture, animal fur and other major diseases. IgY could effectively prevent and treat animal diseases, but also reduce the possibility of zoonosis, which will be of great significance for the protection of personal safety.

Key words: immunoglobulin of yolk(IgY); application; animal disease; human disease; zoonoses; prospects

中图分类号:

S852.4

亓秀晔, 宋翔, 王业华, 徐海燕, 程福亮, 谷巍. 卵黄抗体在疾病防制中的应用研究进展[J]. 《中国畜牧兽医》, 2017, 44(9): 2767-2772.

QI Xiu-ye, SONG Xiang, WANG Ye-hua, XU Hai-yan, CHENG Fu-liang, GU Wei. Research Progress on Immunoglobulin of Yolk in the Prevention and Treatment of Various Diseases[J]. , 2017, 44(9): 2767-2772.

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