头孢洛宁的药理作用及其在奶牛乳房炎防治中应用的研究进展

doi:10.16431/j.cnki.1671-7236.2016.10.034

摘要/Abstract

摘要：

头孢洛宁是第2代头孢菌素类抗生素，是防治干乳期奶牛乳腺炎的有效药物，具有抗菌谱广、杀菌力强、过敏反应少、毒性低等优点，尤其对金黄色葡萄球菌、链球菌展现出良好的抗菌活性。文章综述了头孢洛宁的研究现状、理化性质、药理和毒理、药代动力学、残留及弃奶期及其在奶牛乳房炎防治中的应用，并对其应用前景作了展望。

关键词: 头孢洛宁; 乳房炎; 药效; 干乳期; 残留; 临床应用

Abstract:

Cephalonium is a second generation cephalosporin.It is effective to prevent and treat mastitis during dry period.It has a broad antibacterial spectrum,strong bactericidal activity,less allergic reactions and low toxicity,and so on,especially showing a good antibacterial activity to Staphylococcus aureus and Streptococus.In this paper,the physical and chemical properties,pharmacokinetic,pharmacology and toxicology,residue and withdrawal periods,application in the prevention and treatment of mastitis in dairy cows,and the prospect of the development of cephalonium were investigated and reviewed.

Key words: cephalonium; mastitis; efficacy; dry period; residue; clinical application

中图分类号:

S859.79

华伟毅, 刘义明, 徐飞, 李秀波. 头孢洛宁的药理作用及其在奶牛乳房炎防治中应用的研究进展[J]. 《中国畜牧兽医》, 2016, 43(10): 2742-2747.

HUA Wei-yi, LIU Yi-ming, XU Fei, LI Xiu-bo. Research Progress on Pharmacological Action of Cephalonium and Its Application in Prevention and Treatment of Mastitis in Dairy Cow[J]. , 2016, 43(10): 2742-2747.

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