中国畜牧兽医 ›› 2021, Vol. 48 ›› Issue (3): 1027-1033.doi: 10.16431/j.cnki.1671-7236.2021.03.027

• 预防兽医 • 上一篇    下一篇

公英翘芦散治疗亚临床型奶牛乳房炎的效果研究

张鹏举, 付丽云, 陈志强, 尚静雪, 张远达, 蔡小利, 战文   

  1. 内蒙古华天制药有限公司, 赤峰 024070
  • 收稿日期:2020-07-14 出版日期:2021-03-20 发布日期:2021-03-18
  • 通讯作者: 陈志强 E-mail:Zhq chen@163.com
  • 作者简介:张鹏举(1994-),男,内蒙古赤峰人,本科,研究方向:兽药研发,E-mail:1433898081@qq.com
  • 基金资助:
    2018年内蒙古自治区科技重大专项(KJZD2018008)

Study on the Effect of Gongyingqiaolu Powder in Treating Subclinical Cow Mastitis

ZHANG Pengju, FU Liyun, CHEN Zhiqiang, SHANG Jingxue, ZHANG Yuanda, CAI Xiaoli, ZHAN Wen   

  1. Inner Mongolia Huatian Pharmaceutical Co., Ltd., Chifeng 024070, China
  • Received:2020-07-14 Online:2021-03-20 Published:2021-03-18

摘要: 本研究旨在初步考察公英翘芦散对亚临床奶牛乳房炎的临床治疗效果。试验选取78头发病牛,其中38头牛为散发,用公英翘芦散治疗;40头牛集中对比治疗,随机分成2组,每组20头,分别用公英翘芦散和公英散进行治疗。用加州乳房炎检验(California mastitis trial,CMT)法检测公英翘芦散治疗后乳区患病状态并判定其治疗效果;用体细胞计数(somatic cell count,SCC)法检测公英翘芦散和公英散治疗后牛奶体细胞数并判定其治疗效果。结果显示,公英翘芦散给药7 d后,患病乳区由75个减少到28个,治疗效果非常显著,治愈率达到62.67%,有效率达到90.67%。与治疗前相比,公英翘芦散和公英散用药1 d后体细胞数均极显著降低(P<0.01),且公英翘芦散组SCC下降幅度明显超过公英散组。公英翘芦散组在给药2 d后体细胞数显著低于公英散组(P<0.05),给药3 d之后均极显著低于公英散组(P<0.01)。用药7 d后,公英翘芦散组治愈率可达68.29%,而公英散组治愈率只达到20.00%,差异极显著(P<0.01);公英翘芦散组有效率可达97.56%,而公英散组有效率为67.50%,差异极显著(P<0.01),说明公英翘芦散的治疗效果极显著优于公英散(P<0.01)。以上结果说明,公英翘芦散可以作为治疗亚临床奶牛乳房炎的有效药物,为奶牛乳房炎药物的开发提供参考。

关键词: 亚临床型奶牛乳房炎; 公英翘芦散; 体细胞计数法; 加州乳房炎检验法

Abstract: The purpose of this study was to investigate the clinical effect of Gongyingqiaolu powder on subclinical mastitis of dairy cow.In this experiment,78 cattle were selected,38 of which were sporadic and treated with Gongyingqiaolu powder,another 40 cattle were treated with concentrated contrast treatment and randomly divided into 2 groups with 20 cattle in each group,which were treated with Gongyingqiaolu powder and Gongying powder respectively.The California mastitis trial (CMT) method was used to detect the disease status of the udder after the treatment of Gongyingqiaolu powder and determined its therapeutic effect.Somatic cell count (SCC) method was used to detect the somatic cell number of milk after treatment with Gongyingqiaolu powder and Gongying powder and determined the therapeutic effect.The results showed that after 7 d of treatment with Gongyingqiaolu powder and Gongying powder,the number of affected udder was reduced from 75 to 28,and the treatment effect was very significant,with the cure rate reaching 62.67% and the effective rate reaching 90.67%.Compared with untreatment group,the number of somatic cells after 1 d of treatment with Gongyingqiaolu powder and Gongying powder was extremely significantly decreased (P<0.01),and the SCC of Gongyingqiaolu powder group decreased significantly than that of Gongying powder group.Compared with Gongying powder group,the SCC of Gongyingqiaolu powder group decreased significantly after 2 d of administration (P<0.05),and extremely significantly decreased after 3 d of administration (P<0.01).After 7 d of treatment,the cure rate of Gongyingqiaolu powder group reached 68.29%,while the cure rate of Gongying powder group only reached 20.00%,with a extremely significant difference (P<0.01).The effective rate of Gongyingqiaolu powder group was 97.56%,while the effective rate of Gongying powder group was 67.50%,the difference was extremely significant (P<0.01),indicating that the therapeutic effect of Gongyingqiaolu powder was extremely significantly better than that of Gongying powder (P<0.01).The above results indicated that Gongyingqiaolu powder could be used as an effective drug to treat subclinical cow mastitis and provided a reference for the development of cow mastitis drugs.

Key words: subclinical cow mastitis; Gongyingqiaolu powder; somatic cell number; California mastitis trial

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