›› 2018, Vol. 45 ›› Issue (11): 3271-3278.doi: 10.16431/j.cnki.1671-7236.2018.11.035

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Research Progress on Coating Technologies to Improve Pharmaceutical Pharmacy Performance

LI Chao, LUO Wanhe, ZHOU Kaixiang, CHEN Dongmei, PAN Yuanhu, TAO Yanfei, XIE Shuyu   

  1. National Reference Laboratory of Veterinary Drug Residues, Huangzhong Agricultural University, Wuhan 430070, China
  • Received:2018-04-19 Online:2018-11-20 Published:2018-11-20

Abstract:

Veterinary medicine is of great significance in the prevention and control of diseases and healthy breeding in animal husbandry production.However,it is limited in clinical use due to poor palatability,large irritation to gastric mucosa,poor stability,and poor targeting of infection sites of certain drugs.Coating technology has significant advantages in improving drug palatability,improving drug stability and preparing controlled release and targeted dosage forms.This article summarizes the research progress on coating technology at home and abroad to improve drug palatability,improve drug stability,preparation of control and sustained-release formulations and efficient targeted drug delivery,analyzes the principle of the formation of coating film,the advantages and disadvantages of several common coating technologies and the challenges faced by their industrialization and looks forward to the application of coating technology in the field of veterinary medicine,it is respected to provide new ideas for the development of veterinary drug formulations based on coating technologies.

Key words: coating technologies; drug; palatability; controlled release; target

CLC Number: