Toll样受体在哺乳动物排卵过程中的生物学作用

doi:10.16431/j.cnki.1671-7236.2016.06.029

Abstract

Abstract: Toll-like receptors (TLRs) is the main category of pattern recognition receptors.It is not only expressed in classical immune cells,but also expressed in the ovary and the genital tract of a variety of mammals.It plays an important role in ovarian activities.Biological functions of TLRs in the ovulation processes is the main research content in the field of reproductive immunology because that ovulation is a core event in ovarian activities and the key to determine the success or failure of reproductive.This review will concentrate on expression and distribution of TLRs in mammalian ovary,regulation mechanisms of TLRs expression and function,and the functions and significance of the ovulation process.Then we analyze briefly its possible functions in ovulation-related diseases.We want to provide a reference in research areas of reproductive immunology.

Key words: TLRs; mammals; ovulation; regulation; biological functions

CLC Number:

S814

JIA Sheng-jun, ZHAO Jiao, LI Na. Biological Functions of TLRs in Mammalian Ovulation Processes[J]. , 2016, 43(6): 1591-1596.

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Biological Functions of TLRs in Mammalian Ovulation Processes

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