北京市伴侣动物源肠球菌的抗菌药物耐受情况调查

doi:10.16431/j.cnki.1671-7236.2020.12.036

Abstract

Abstract: In order to study the tolerance of Enterococcus spp.from companion animals to common antibiotics in Beijing,320 samples were collected from dogs and cats in a pet hospital in Beijing from May 2015 to January 2016.The strains were isolated by selective culture medium and identified by VITEK-2 Compact 60.The sensitivity test of 11 kinds of common antibiotics in 8 categories was carried out for the isolated and identified strains.At the same time,the high-level gentamicin and high-level streptomycin resistance test were carried out to analyze the drug resistance and multiple drug resistance of Enterococcus.A total of 318 strains of non repetitive enterococci with different colony morphology and biochemical characteristics were obtained.The isolation rates of Enterococcus faecalis (49.06%) and Enterococcus faecium (29.87%) were higher.The resistance rates of Enterococcus to high-level gentamicin and high-level streptomycin were 39.94% and 43.40%,respectively.The resistance rates to tetracycline (78.62%),erythromycin (67.30%) and quinoproptin dapfoptin (43.71%) were very high.All of them were sensitive to tigecycline,and the non-resistant rate to vancomycin and nitrofurantoin was also high (98.74%).Enterococcus tested showed different degrees of resistance to class 1 to class 7 antibiotics,and the multidrug resistance was common,and the multidrug resistance rate was as high as 57.23%.The number of resistant antibiotics was the highest (n=65).A total of 44 different drug resistance profiles were obtained.Among them,erythromycin-quinoptin-daptoptin-tetracycline-high level aminoglycoside resistant spectrum accounted for the highest proportion (45/318,14.15%).This study confirmed that Enterococcus spp.isolated from companion animals in Beijing was highly resistant to common antibiotics,and multidrug resistance was prevalent.Therefore,it was necessary to strengthen the monitoring of drug resistance.

Key words: companion animals; Enterococcus spp.; drug resistance; multidrug resistance

CLC Number:

S852.61⁺1

CHEN Xia, ZHAO Xiaofei, BAI Xuemei, CHE Jie, ZHANG Yunfei, YUAN Min, LI Juan. Research on Antimicrobial Resistance Characteristics of Enterococcus spp. from Companion Animals in Beijing[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(12): 4119-4126.

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Research on Antimicrobial Resistance Characteristics of Enterococcus spp. from Companion Animals in Beijing

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