猪血凝性脑脊髓炎病毒不同佐剂灭活疫苗免疫BALB/c小鼠的比较试验

›› 2009, Vol. 36 ›› Issue (6): 34-37.

• 生理生化 • Previous Articles Next Articles

Comparison of Different Adjuvant Inactive Vaccines for Hemagglutinating Encephalomyelitis Virus Immunizing BALB/c Mice

CHEN Ke-yan¹，HE Wen-qi¹，LU Hui-jun²ZHAO Kui¹，ZHAO Chuan-bo¹，ZENG Fan-qin¹，GAO Feng¹

（1.College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China;2.Key Laboratory of Zoonoses, Ministry of Education, Institute of Zoonoses, Jilin University, Changchun 130062, China）

Received:1900-01-01 Revised:1900-01-01 Online:2009-06-20 Published:2009-06-20
Contact: GAO Feng

Abstract

Abstract: The BALB/c mice were immunized with HEV inactive vaccines of two kinds of adjuvant, Al(OH)₃ assistant inactive vaccine and propolis assistant inactive vaccine. The serum samples from mice were monitored with hemagglutination inhibition（HI）test. Comparison of different adjuvant effect was analyzed according to antibody titer of mice. The results showed that Al(OH)₃ assistant inactive vaccine stimulated early immune response and produced a continuous and high level antibody. The vaccine candidacy of HEV inactivated vaccine with Al(OH)₃adjuvant was proposed.

Key words: hemagglutinating encephalomyelitis virus; inactivated vaccine; adjuvant

CLC Number:

S859.79

CHEN Ke-yan;HE Wen-qi;LU Hui-junZHAO Kui;ZHAO Chuan-bo;ZENG Fan-qin;GAO Feng. Comparison of Different Adjuvant Inactive Vaccines for Hemagglutinating Encephalomyelitis Virus Immunizing BALB/c Mice[J]. , 2009, 36(6): 34-37.

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Comparison of Different Adjuvant Inactive Vaccines for Hemagglutinating Encephalomyelitis Virus Immunizing BALB/c Mice

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