miRNA对乳腺发育及泌乳调节作用的研究进展

doi:10.11843/j.issn.1671-7236.2015.03.024

Abstract

Abstract: microRNAs (miRNAs) are non-coding RNAs that play important roles in post transcriptional regulation of gene expression,there are a large number of studies have shown that,miRNA involved in regulating a variety of life activities,including the formation of cell proliferation and differentiation,hormone secretion,metabolism,the formation and development of muscle and fat,immune response,and tumor formation and other diseases.In recent years,miRNA has become a bright spot in the life science research.With the discovery of miRNA and its functional study in-depth,the relevant research of breast growth and lactation regulation has entered a new level of miRNA regulation.This article summarizes the miRNA stage-specific expression in mammary gland development and lactation process and differences in health breast and breast lesions when miRNA expression,reviewed the regulation effect of miRNA on mammary gland development and lactation,for the purpose of providing new ideas from the miRNA level on mammary development and lactation.

Key words: miRNA; mammary gland development; lactation

CLC Number:

Q522

ZHANG Shu, ZHANG Qiang, ZHANG Meng, YANG Jian-cheng. Research Progress on Regulation Effect of microRNA on Mammary Gland Development and Lactation[J]. , 2015, 42(3): 663-667.

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Research Progress on Regulation Effect of microRNA on Mammary Gland Development and Lactation

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