1 王明俊. 兽医生物制品学[M]. 北京: 中国农业出版社,1997. 2 王永录, 张永光, 方玉珍, 等. 牛O-A型口蹄疫双价灭活苗研究: 效力试验和最小免疫剂量试验[J]. 中国兽医科技,1999, 29 (9): 3~4. 3 张永光, 王永录, 方玉珍, 等. 牛O-A型口蹄疫双价灭活苗研究: 疫苗制备及其安全效力试验[J]. 中国兽医科技, 1996, 26 (5): 3~5. 4 杨永钦,李乐.口蹄疫疫苗Asia 1型灭活苗的研究[J].中国畜禽传染病, 1995, 82(3):29~30. 5 殷震, 刘景华. 动物病毒学[M]. 第2版. 北京: 科学出版社,1997. 6 Alejo D M,Moraes M P,Liao X, et al. An adenovirus vectored mucosal adjuvant augments protection of mice immunized intranasally with an adenovirus-vectored foot-and-mouth disease virus subunit vaccine[J].Vaccine, 2013, 31 (18): 2302~2309. 7 Bahnemann H G. Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production[J]. Arch Virol, 1975, 47(1):47~56. 8 Brown F, Newman J F. In vitro measurement of the potency of inactivated foot-and-mouth disease virus vaccines[J]. J Hyg, 1963, 61:345~351. 9 Carrillo C, Wigdorovitz A, TronoK, et al. Induction of a virus specific antibody response to foot-and-mouth disease virus using the structural protein VP1 expressed in transgenic potatoes plants[J]. Virol Immunol, 2001, 14: 49~57. 10 Chan E W, Wong H T, Cheng S C, et al. An immunoglobulin G based chimeric protein induced foot-and-mouth disease specific immune response in swine[J]. Vaccine, 2000, 19(4~5): 538~546. 11 Chinsangaram J, Beard C, Mason P W, et al. Antibody response in mice inoculated with DNA expressing foot-and-mouth disease virus capsid proteins[J]. J Virol,1998, 72(5):4454~4457. 12 Du Y, Jiang P, Li Y, et al. Immune responses of two recombinant adenoviruses expressing VP1 antigens of FMDV fused with porcine granulocyte macrophage colony-stimulating factor[J]. Vaccine, 2007, 25(49): 8209~8219. 13 Frenkel H S. The cultivation of the virus on a practical scale in explantation bovine tongue epithelium[J]. Am J Vet Res,1951, 17(3):224~228. 14 Fowler V, Robinson L, Bankowski B, et al. A DNA vaccination regime including protein boost and electroporation protects cattle against foot-and-mouth disease[J]. Antiviral Res,2012, 94(1): 25~34. 15 Grubman M J, Moraes M P, Schutta C, et al. Adenovirus serotype 5-vectored foot-and-mouth disease subunit vaccines: the first decade[J]. Future Virol, 2010, 5(1): 51~64. 16 Lombard M, Pastoret P P, Moulin A M. A brief history of vaccines and vaccination[J]. Rev Sci Tech, 2007, 26(1): 29~48. 17 Li Y, Stirling C M, Denyer M S, et al. Dramatic improvement in FMD DNA vaccine efficacy and cross-serotype antibody induction in pigs following a protein boost[J]. Vaccine, 2008, 26(21):2647~2656. 18 Li P, Zhang Y G, Wang Y L, et al. Foliar extracts from transgenic tomato plants expressing the structural poly protein, P1-2A, and protease, 3C, from foot-and-mouth disease virus elicit a protective response in guinea pigs[J]. Vet Immunol Immunopathol, 2008, 121(1): 83~90. 19 Moraes M P, Mayr G A, Mason P W, et al. Early protection against homologous challenge after a single dose of replication-defective human adenovirus type 5 expressing capsid proteins of foot-and-mouth disease virus (FMDV) strain A24[J]. Vaccine,2002, 20(11~12): 1631~1639. 20 Pacheco J M, Brum M C, Moraes M P, et al. Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit vaccine[J]. Virology, 2005, 337(2): 205~209. 21 Pacheco J M. Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit vaccine[J]. Virology, 2005, 337(2): 205~209. 22 Rao J P,Agrawal P,Mohammad R,et al. Expression of VP1 protein of serotype A and O of foot-and-mouth disease virus in transgenic sunnhemp plants and its immunogenicity for guinea pigs[J]. Acta Virol,2012, 56(2):91~99. 23 Sanz-Parra A,Jimenez-Clavero M A, Garcia-Briones M M, et al. Recombinant viruses expressing the foot-and-mouth disease virus capsid precursor polypeptide P1 induce cellular but not homoral antiviral immunity and partial protection in pigs[J]. Virology, 1999, 259(1): 129~134. 24 Taboga O, Tami C, Carrillo E, et al. A large-scale evaluation of peptide vaccines against foot-and-mouth disease: Lack of solid protection in cattle and isolation of escape mutants[J]. J Virol, 1997, 71(4): 2606~2614. 25 Ward G, Rieder E, Mason P W. Plasmid DNA encoding replicating foot-and-mouth disease virus genomes induces antiviral immune responses in swine[J]. J Virol, 1997, 71(10): 7442~7447. 26 Yang N S, Wang J H, Lin K F, et al. Comparative studies of the capsid precursor polypeptide P1 and the capsid protein VP1 cDNA vectors for DNA vaccination against foot-and-mouth disease virus[J]. J Gene Med, 2005, 7(6): 708~717. 27 Yu X, Xiao S, Jiang Y, et al. A DNA vaccine encoding the FMDV capsid precursor polypeptide P1 and the enhancing effect of bovine herpesvirus 1 VP22 protein as molecular adjuvant[J].Acta Virol, 2012, 56(2):111~117. 28 Zhou G, Wang H, Wang F, et al. Recombinant adenovirus expressing type Asia 1 foot-and-mouth disease virus capsid proteins induces protective immunity against homologous virus challenge in mice[J]. Res Vet Sci, 2013, 94(3):796~802. |